Effect of an Increase in Left Ventricular Pressure Overload on Left Atrial-Left Ventricular Coupling in Patients with Hypertension: A Two-Dimensional Speckle Tracking Echocardiographic Study

• Published in: Echocardiography (Mount Kisco, N.Y.) N.Y.), 2013-07, Vol.30 (6), p.658-666
• Main Authors: Miyoshi, Hirokazu, Oishi, Yoshifumi, Mizuguchi, Yukio, Iuchi, Arata, Nagase, Norio, Ara, Nusrat, Oki, Takashi
• Format: Article
• Language: English
• Subjects: Causality; Comorbidity; diastolic function; Echocardiography - methods; Echocardiography - statistics & numerical data; Elastic Modulus; Elasticity Imaging Techniques - methods; Elasticity Imaging Techniques - statistics & numerical data; Female; Humans; hypertension; Hypertension - diagnostic imaging; Hypertension - epidemiology; Hypertension - physiopathology; Japan - epidemiology; left atrium; Male; Middle Aged; Prevalence; Reproducibility of Results; Risk Factors; Sensitivity and Specificity; strain-strain rate; Ventricular Dysfunction, Left - diagnostic imaging; Ventricular Dysfunction, Left - epidemiology; Ventricular Dysfunction, Left - physiopathology
• ISSN: 0742-2822; 1540-8175
• DOI: 10.1111/echo.12117

Background Two‐dimensional speckle tracking echocardiography (2DSTE) has recently been applied to evaluate left atrial (LA) function in addition to left ventricular (LV) function. However, whether 2DSTE can provide insight into LA‐LV interaction related to an increase in LV pressure overload remains unknown. Methods One hundred five asymptomatic patients with hypertension were studied by conventional, pulsed and tissue Doppler, and 2DSTE. Hypertensive patients were classified into 2 groups according to the ratio of early diastolic to atrial systolic velocity (E/A) of transmitral flow: E/A ≥ 1 (n = 37) and E/A