Screening of hallucinogenic mushrooms with high-performance liquid chromatography and multiple detection

A rapid, sensitive and specific method for the screening of hallucinogenic mushrooms has been developed. High-performance liquid chromatography with simultaneous use of ultraviolet, fluorescence and electrochemical detection was employed. Separation of the mushroom components was achieved on a silic...

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Bibliographic Details
Published in:Journal of Chromatography A 1983-01, Vol.270, p.293-299
Main Authors: Christiansen, A.L., Rasmussen, K.E.
Format: Article
Language:English
Subjects:
alkaloids
baeocystin
Biological and medical sciences
Drug addictions
high-performance liquid chromatography
Medical sciences
psilocin
Psilocybe
psilocybin
Toxicology
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Summary:A rapid, sensitive and specific method for the screening of hallucinogenic mushrooms has been developed. High-performance liquid chromatography with simultaneous use of ultraviolet, fluorescence and electrochemical detection was employed. Separation of the mushroom components was achieved on a silica column using an alkaline aqueous methanolic eluent. The use of detector response ratios for identification of hallucinogenic indole alkaloids has been evaluated.
ISSN:0021-9673
DOI:10.1016/S0021-9673(01)96375-7