In utero exposure of bovine fetuses to polychlorinated biphenyls [Cows, contaminated silage, toxicity]

Pregnant mature beef cows more than 6 mo from parturition were fed whole plant corn silage from either a silo (contaminated) that had been coated with a plastic containing polychlorinated biphenyls (Aroclor 1254) or from a silo (clean) that had not been coated with the plastic. In addition, a third...

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Bibliographic Details
Published in:Journal of dairy science 1984-01, Vol.67 (1), p.224-228
Main Authors: Perry, T.W, Everson, R.J, Hendrix, K.S, Peterson, R.C, Robinson, F.R
Format: Article
Language:English
Subjects:
Adipose Tissue - analysis
Animal Feed - analysis
Animals
Aroclors - analysis
Aroclors - metabolism
Cattle - embryology
Chlorodiphenyl (54% Chlorine)
Female
Fetus - metabolism
Food Contamination - analysis
Liver - analysis
Male
Maternal-Fetal Exchange
Milk - analysis
Polychlorinated Biphenyls - metabolism
Pregnancy
Thyroid Gland - analysis
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Summary:Pregnant mature beef cows more than 6 mo from parturition were fed whole plant corn silage from either a silo (contaminated) that had been coated with a plastic containing polychlorinated biphenyls (Aroclor 1254) or from a silo (clean) that had not been coated with the plastic. In addition, a third group of cows was fed silage from the clean silo plus 200 mg Aroclor 1254 per head daily (added polychlorinated biphenyls). After 30 days on treatment, one cow from each of the three treatments had her fetus removed by Caesarean section for assay of liver, thyroid, and fat for polychlorinated biphenyls content. Tissue content of polychlorinated biphenyls for fetuses from cows fed clean silage, contaminated silage, or added polychlorinated biphenyls was (microgram/g): liver, 3.6, 4.7, and 54.1; thyroid, 2.3, 19.4, and 121.1; fat, .65, 18.1, and 130.6, indicating polychlorinated biphenyls cross the placenta readily. Cow milk (colostrum) contents of polychlorinated biphenyls on the 1st day following parturition for the three respective treatments were .54, 8.5, and 96.4 micrograms/g (clean silage, contaminated silage, and added polychlorinated biphenyls). Fetuses taken from cows that had been removed from polychlorinated biphenyl exposure for 6 mo reflected previous treatments of dams by increased fetal fat stores of polychlorinated biphenyls.
ISSN:0022-0302
1525-3198
DOI:10.3168/jds.S0022-0302(84)81289-8