The effects of oxygen partial pressure changes on the osteometric markers of the bone tissue in rats

Our purpose was to investigate the oxygen partial pressure changes on the osteometric and biochemical markers of bone tissue in rats. It was shown that breathing of altered gas mixture did not change the mass, general length, sagittal diameter and density thigh-bones in 12-month Wistar male-rats. Th...

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Bibliographic Details
Published in:Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) Ukraine : 1994), 2013, Vol.59 (2), p.47-51
Main Authors: Berezovs'kyĭ, V Ia, Zamors'ka, T M, Ianko, R V
Format: Article
Language:eng ; ukr
Subjects:
Acid Phosphatase - metabolism
Alkaline Phosphatase - metabolism
Animals
Bone Density - physiology
Bone Regeneration - physiology
Bones of Lower Extremity - anatomy & histology
Bones of Lower Extremity - enzymology
Hypoxia - enzymology
Hypoxia - physiopathology
Isoenzymes - metabolism
Male
Oxygen - metabolism
Partial Pressure
Rats
Rats, Wistar
Tartrate-Resistant Acid Phosphatase
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Summary:Our purpose was to investigate the oxygen partial pressure changes on the osteometric and biochemical markers of bone tissue in rats. It was shown that breathing of altered gas mixture did not change the mass, general length, sagittal diameter and density thigh-bones in 12-month Wistar male-rats. The dosed normobaric hypoxia increased the activity of alkaline phosphatase and decreased the activity of tartrate-resistant acid phosphatase. At the same time normobaric hyperoxia with 40 and 90% oxygen conversely decreased the activity of alkaline phosphatase and increased the activity of tartrate-resistant acid phosphatase.
ISSN:2522-9028
2522-9036
DOI:10.15407/fz59.02.047