Association of implantable defibrillator therapy risk with body mass index in systolic heart failure

Abstract Objectives To determine whether risk for implantable cardioverter-defibrillator (ICD) therapy varies by body mass index (BMI) in systolic heart failure (HF). Background It is unknown whether obesity increases sudden death risk in patients with systolic HF. Methods Secondary analysis of pati...

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Bibliographic Details
Published in:Heart & lung 2013-07, Vol.42 (4), p.257-261
Main Authors: Gandhi, Mitul, MD, Koelling, Todd M., MD, Pelosi, Frank, MD, Patel, Shaun P., MD, Wojcik, Brandon M., MD, Horwood, Laura E., MS, NP, Wu, Audrey H., MD, MPH
Format: Article
Language:English
Subjects:
Aged
Body Mass Index
Cardiac arrhythmia
Cardiovascular
Critical Care
Death, Sudden, Cardiac - etiology
Defibrillators, Implantable
Female
Heart failure
Heart Failure, Systolic - complications
Humans
Implantable cardioverter-defibrillator
Male
Middle Aged
Obesity
Overweight - complications
Proportional Hazards Models
Pulmonary/Respiratory
Risk Factors
Risk stratification
Therapy
Ventricular Dysfunction, Left - complications
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Summary:Abstract Objectives To determine whether risk for implantable cardioverter-defibrillator (ICD) therapy varies by body mass index (BMI) in systolic heart failure (HF). Background It is unknown whether obesity increases sudden death risk in patients with systolic HF. Methods Secondary analysis of patients with HF, left ventricular ejection fraction ≤0.40 and ICD ( N  = 464) was performed using Cox regression modeling to assess risk for first delivered ICD therapy, with patients grouped by BMI (kg/m2 ): normal (18.5 to
ISSN:0147-9563
1527-3288
DOI:10.1016/j.hrtlng.2012.12.008