Radiation-induced valvular dysfunction

Radiation-induced heart disease is a well described entity. Previous reports have concentrated on the effects of radiation on the pericardium and myocardium causing pericarditis and myocardial fibrosis. In the last decade, some investigators have described valvular thickening, fibrosis and regurgita...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 1983-07, Vol.2 (1), p.180-185
Main Authors: Warda, Mamdouh, Khan, Attiya, Massumi, Ali, Mathur, Virendra, Klima, Tomas, Hall, Robert J.
Format: Article
Language:English
Subjects:
Aortic Valve Stenosis - etiology
Aortic Valve Stenosis - pathology
Aortic Valve Stenosis - physiopathology
Endocardium - pathology
Humans
Myocardium - pathology
Pericarditis, Constrictive - etiology
Pericarditis, Constrictive - pathology
Radiotherapy - adverse effects
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Summary:Radiation-induced heart disease is a well described entity. Previous reports have concentrated on the effects of radiation on the pericardium and myocardium causing pericarditis and myocardial fibrosis. In the last decade, some investigators have described valvular thickening, fibrosis and regurgitation. This report presents experience with two patients with aortic valvular stenosis of hemodynamic significance, possibly caused by mediastinal radiation.
ISSN:0735-1097
1558-3597
DOI:10.1016/S0735-1097(83)80390-8