Managing bone and joint infection in children

There is little high quality evidence on which to base the management of bone and joint infections in children. This pragmatic practice note aims to provide a consensus framework of best current practice prior to the availability of data from large national randomised controlled trials. For straight...

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Bibliographic Details
Published in:Archives of disease in childhood 2012-06, Vol.97 (6), p.545-553
Main Authors: Faust, Saul N, Clark, Julia, Pallett, Ann, Clarke, Nicholas M P
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - therapeutic use
Arthritis, Infectious - diagnosis
Arthritis, Infectious - microbiology
Arthritis, Infectious - therapy
Biological and medical sciences
Care and treatment
Child
Diseases of the osteoarticular system
General aspects
Humans
Individualized Instruction
Infectious bone diseases
Intravenous therapy
Medical case management
Medical sciences
Methods
Miscellaneous
Miscellaneous. Osteoarticular involvement in other diseases
Neonates
Osteomyelitis - diagnosis
Osteomyelitis - microbiology
Osteomyelitis - therapy
Prevention and actions
Public health. Hygiene
Public health. Hygiene-occupational medicine
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Summary:There is little high quality evidence on which to base the management of bone and joint infections in children. This pragmatic practice note aims to provide a consensus framework of best current practice prior to the availability of data from large national randomised controlled trials. For straightforward infection in previously normal children, recent trends suggest that shorter length of intravenous therapy with switch to oral treatment is acceptable, although this is not the case for the management of complex infections including those with multifocal disease, significant bone destruction, resistant or unusual pathogens, sepsis or in immunosuppressed children. Flowsheets for management based on the evidence reviewed are presented.
ISSN:0003-9888
1468-2044
DOI:10.1136/archdischild-2011-301089