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Thrombocytopenia in Plasmodium vivax Malaria Is Related to Platelets Phagocytosis. e63410

Background Although thrombocytopenia is a hematological disorder commonly reported in malarial patients, its mechanisms are still poorly understood, with only a few studies focusing on the role of platelets phagocytosis. Methods and Findings Thirty-five malaria vivax patients and eight healthy volun...

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Published in:PloS one 2013-05, Vol.8 (5)
Main Authors: Coelho, Helena CristinaC, Lopes, Stefanie CP, Pimentel, Joao PauloD, Nogueira, Paulo A, Costa, Fabio TM, Siqueira, Andre M, Melo, Gisely C, Monteiro, Wuelton M, Malheiro, Adriana, Lacerda, Marcus VG
Format: Article
Language:English
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Summary:Background Although thrombocytopenia is a hematological disorder commonly reported in malarial patients, its mechanisms are still poorly understood, with only a few studies focusing on the role of platelets phagocytosis. Methods and Findings Thirty-five malaria vivax patients and eight healthy volunteers (HV) were enrolled in the study. Among vivax malaria patients, thrombocytopenia (
ISSN:1932-6203
DOI:10.1371/journal.pone.0063410