Epidemiology and risk factors for chronic kidney disease in patients with ischaemic stroke

Background There is growing evidence for an association between chronic renal disease (CKD) and adverse cerebrovascular events because of the overlap of several risk factors. The purpose of this study is to examine the epidemiology of CKD and the characteristics of risk factors for CKD in the popula...

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Bibliographic Details
Published in:European journal of clinical investigation 2013-08, Vol.43 (8), p.829-835
Main Authors: Bao, Yu-Shi, Song, Li-Ting, Zhong, Di, Song, A-Xia, Jia, Xi-Bei, Liu, Rui-Chan, Xie, Ru-Juan, Na, Shi-Ping
Format: Article
Language:English
Subjects:
China - epidemiology
Chronic kidney disease
Diabetic Nephropathies - complications
Diabetic Nephropathies - epidemiology
epidemiology
Female
Glomerular Filtration Rate - physiology
Humans
Hypertension - complications
Hypertension - epidemiology
ischaemic stroke
Male
Middle Aged
Regression Analysis
Renal Insufficiency, Chronic - complications
Renal Insufficiency, Chronic - epidemiology
Renal Insufficiency, Chronic - physiopathology
Retrospective Studies
risk factor
Risk Factors
Stroke - complications
Stroke - epidemiology
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Summary:Background There is growing evidence for an association between chronic renal disease (CKD) and adverse cerebrovascular events because of the overlap of several risk factors. The purpose of this study is to examine the epidemiology of CKD and the characteristics of risk factors for CKD in the population with ischaemic stroke. Methods This retrospective study included 571 patients with ischaemic stroke. Estimated glomerular filtration rate (eGFR) was calculated by the Modification of Diet in Renal Disease (MDRD) study equation. Renal function was assessed according to the Kidney Disease Outcomes Quality Initiative (K/DOQI)‐CKD classification. Results Study demonstrated that the major factors associated with CKD in the ischaemic stroke patients were age, diabetes mellitus, hypertension, systolic blood pressure, LDL cholesterol and serum uric acid. Diabetes mellitus (OR 4·146, 95% CI 1·047–16·418, P = 0·043), hypertension and diabetes mellitus (OR 3·574, 95% CI 1·248–10·234, P = 0·018), serum uric acid (OR 1·010, 95% CI 1·006–1·013, P 
ISSN:0014-2972
1365-2362
DOI:10.1111/eci.12113