Scleroderma renal crises: case report and review of literature

Scleroderma (systemic sclerosis) is a connective tissue disorder which involves skin, gastrointestinal tract, kidneys and lungs with considerable morbidity. Scleroderma renal crisis is a well-known severe form of renal involvement, characterised by the presence of high blood pressure with variable d...

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Bibliographic Details
Published in:Journal of the Pakistan Medical Association 2013-07, Vol.63 (7), p.916-918
Main Authors: Sabir, Omer, Younas, Haroon, Tanvir, Imrana, Tarif, Nauman
Format: Article
Language:English
Subjects:
Biopsy
Blood Pressure
Diagnosis
Diagnosis, Differential
Humans
Hypertension
Kidney Diseases - diagnosis
Kidney Diseases - etiology
Kidney Diseases - physiopathology
Kidney Glomerulus - pathology
Male
Middle Aged
Scleroderma (Disease)
Scleroderma, Systemic - complications
Scleroderma, Systemic - diagnosis
Skin
Skin - pathology
Systemic scleroderma
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Summary:Scleroderma (systemic sclerosis) is a connective tissue disorder which involves skin, gastrointestinal tract, kidneys and lungs with considerable morbidity. Scleroderma renal crisis is a well-known severe form of renal involvement, characterised by the presence of high blood pressure with variable degrees of renal insufficiency. We report a case of scleroderma renal crisis diagnosed on the basis of history of scleroderma, high blood pressure and renal dysfunction. The biopsy confirmed the typical histopathological findings. We discuss herein the management of the case and review the literature.
ISSN:0030-9982