Motors and MAPs Collaborate to Size Up Microtubules

Midzone microtubules keep chromosomes apart after segregation and provide a platform for cytokinesis factors. Reporting recently in Cell, Subramanian et al. (2013) describe how the motor protein kinesin-4 and the microtubule-associated protein PRC1 work together to mark microtubule ends for incorpor...

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Bibliographic Details
Published in:Developmental cell 2013-07, Vol.26 (2), p.118-120
Main Authors: Bechstedt, Susanne, Brouhard, Gary J.
Format: Article
Language:English
Subjects:
Cell Cycle Proteins - metabolism
Humans
Microtubules - metabolism
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Summary:Midzone microtubules keep chromosomes apart after segregation and provide a platform for cytokinesis factors. Reporting recently in Cell, Subramanian et al. (2013) describe how the motor protein kinesin-4 and the microtubule-associated protein PRC1 work together to mark microtubule ends for incorporation into the midzone in a length-dependent manner.
ISSN:1534-5807
1878-1551
DOI:10.1016/j.devcel.2013.07.010