Patent foramen ovale closure in the treatment of obstructive sleep apnea

Obstructive sleep apnea (OSA) and patent foramen ovale (PFO) are common conditions and may coexist. In patients with OSA, increases in right-to-left shunting across a PFO may result in increased burden of hypoxia, although the effect of this is unknown. We report the cases of 3 patients with highly...

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Bibliographic Details
Published in:The Journal of invasive cardiology 2013-08, Vol.25 (8), p.E169-E171
Main Authors: White, Jonathon M, Veale, Andrew G, Ruygrok, Peter N
Format: Article
Language:English
Subjects:
Adult
Cardiac Catheterization - methods
Comorbidity
Continuous Positive Airway Pressure
Foramen Ovale, Patent - epidemiology
Foramen Ovale, Patent - physiopathology
Foramen Ovale, Patent - therapy
Humans
Hypoxia - epidemiology
Hypoxia - physiopathology
Male
Middle Aged
Prevalence
Sleep Apnea, Obstructive - epidemiology
Sleep Apnea, Obstructive - physiopathology
Sleep Apnea, Obstructive - therapy
Stents
Treatment Outcome
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Description
Summary:Obstructive sleep apnea (OSA) and patent foramen ovale (PFO) are common conditions and may coexist. In patients with OSA, increases in right-to-left shunting across a PFO may result in increased burden of hypoxia, although the effect of this is unknown. We report the cases of 3 patients with highly symptomatic OSA and PFO who underwent percutaneous closure with the Coherex FlatStent PFO Closure System. Although PFO closure can be achieved with minimally invasive techniques and low rates of adverse events, its importance in reducing hypoxia in this population is unknown. PFO closure may result in improvement in apneas and symptoms in selected OSA patients and may impact cardiovascular events in this group through hypoxia-mediated or other unrecognized mechanisms.
ISSN:1557-2501