Critical phase among patients with dengue fever during the 2010 outbreak in Nepal

Background Dengue virus infection has become an increasingly serious threat to public health in Nepal. Detection and/or serotyping of dengue virus has been reported in the past; however, little is known about the critical phase among dengue patients in Nepal. Methods Rapid immunochromatographic test...

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Bibliographic Details
Published in:Transactions of the Royal Society of Tropical Medicine and Hygiene 2013-09, Vol.107 (9), p.598-600
Main Authors: Pun, Sher Bahadur, Shah, Yogendra
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age Factors
Arboviroses
Biological and medical sciences
Child
Dengue - diagnosis
Dengue - epidemiology
Dengue fevers
Disease Outbreaks
Female
General aspects
Human viral diseases
Humans
Infectious diseases
Male
Medical sciences
Middle Aged
Nepal - epidemiology
Reverse Transcriptase Polymerase Chain Reaction
Serotyping
Tropical viral diseases
Viral diseases
Young Adult
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Summary:Background Dengue virus infection has become an increasingly serious threat to public health in Nepal. Detection and/or serotyping of dengue virus has been reported in the past; however, little is known about the critical phase among dengue patients in Nepal. Methods Rapid immunochromatographic tests and reverse transcription PCR (RT-PCR) were performed in order to diagnosis dengue fever. Ultrasonographic and chest radiography were used to identify the plasma leakage phase. Results Of the total 264 patients with dengue, 8.7% (23/264) were admitted during the critical phase; 82.6% (19/23) of the patients were between 20 and 44 years of age. Conclusion Physicians need to be vigilant and attentive to young adult patients with dengue fever.
ISSN:0035-9203
1878-3503
DOI:10.1093/trstmh/trt061