Antibacterial activity, surface roughness, flexural strength, and solubility of conventional luting cements containing chlorhexidine diacetate/cetrimide mixtures

• Published in: The Journal of prosthetic dentistry 2013-08, Vol.110 (2), p.107-115
• Main Authors: Korkmaz, Fatih Mehmet, PhD, Tüzüner, Tamer, PhD, Baygin, Ozgul, PhD, Buruk, Celal Kurtulus, MD, PhD, Durkan, Rukiye, PhD, Bagis, Bora, PhD
• Format: Article
• Language: English
• Subjects: Anti-Bacterial Agents - chemistry; Anti-Bacterial Agents - pharmacology; Cetrimonium Compounds - chemistry; Cetrimonium Compounds - pharmacology; Chlorhexidine - chemistry; Chlorhexidine - pharmacology; Dental Cements - chemistry; Dental Cements - pharmacology; Dentistry; Glass Ionomer Cements - chemistry; Humans; Lactobacillus casei - drug effects; Magnesium Oxide - chemistry; Materials Testing; Pliability; Polycarboxylate Cement - chemistry; Solubility; Streptococcus mutans - drug effects; Stress, Mechanical; Surface Properties; Temperature; Time Factors; Water - chemistry; Zinc Oxide - chemistry; Zinc Phosphate Cement - chemistry
• ISSN: 0022-3913; 1097-6841
• DOI: 10.1016/S0022-3913(13)60349-2

Statement of problem The failure of fixed dental restorations is commonly associated with caries. The use of conventional luting cements containing antibacterial agents may overcome this problem. Purpose The purpose of this study was to evaluate the antibacterial activity (ABA), surface roughness (Ra), flexural strength (FS), and solubility (SL) patterns of the conventional dental luting cements zinc phosphate (ZP), zinc polycarboxylate (PC), and glass ionomer (GIC) after the addition of 5% chlorhexidine diacetate/cetrimide (CHX+CT). Material and methods Antibacterial agents with a total concentration of 5% (2.5% CHX+2.5% CT) were added to antibacterial agent-free conventional luting cement powders (ZPC, PCC, and GICC) and designated as experimental groups (ZPE, PCE, and GICE). ABA against Streptococcus mutans (SM) and Lactobacillus casei (LB) was examined by using the agar diffusion test method. Ra, FS, and SL values were obtained after storage in distilled water at 37°C for 24 hours. The Kruskal-Wallis and Mann Whitney U with Bonferroni correction tests were used to test for agar diffusion (α=.05) and 2-way ANOVA and Fisher Least Significant Difference (LSD) test were used to measure Ra, FS, and SL (α=.05). Results The control groups exhibited limited ABA. With the exception of PCE>PCC on day 1 for SM, all experimental groups showed significantly greater and longer-lasting protection against SM and LB bacteria for up to 180 days than their controls ( P ZPE; P>.05, PCC>PCE; P GICC ( P >.05) when compared with their individual controls. Control groups exhibited higher FS values than did the experimental groups (ZPC>ZPE; P PCE; P GICE; P >.05). The experimental groups exhibited higher solubilities than did their controls in the ZPC ( P >.05) and GICC groups ( P