Role of sympathetic nervous system in protective effects of selectivek-opiate receptor agonist dynorphin A sub(1-13) on the incidence of cardiac arrhythmia during myocardial ischemia

Preliminary administration of dynorphin A sub(1-13) to narcotized cats with myocardial ischemia attenuated cardiac fibrillation, but increased the incidence of ventricular tachycardia. Protective effect of dynorphin A sub(1-13) was observed only under conditions of intact sympathetic cardiac innerva...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2000-01, Vol.129 (1), p.27-29
Main Authors: Mikhailova, S D, Vasil'eva, T V, Semushkina, T M, Storozhakov, GI
Format: Article
Language:English
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Summary:Preliminary administration of dynorphin A sub(1-13) to narcotized cats with myocardial ischemia attenuated cardiac fibrillation, but increased the incidence of ventricular tachycardia. Protective effect of dynorphin A sub(1-13) was observed only under conditions of intact sympathetic cardiac innervation.
ISSN:0007-4888
1573-8221
DOI:10.1007/BF02433859