Identification of a Receptor-Binding Domain in the S Protein of the Novel Human Coronavirus Middle East Respiratory Syndrome Coronavirus as an Essential Target for Vaccine Development

• Published in: Journal of Virology 2013-09, Vol.87 (17), p.9939-9942
• Main Authors: Du, Lanying, Zhao, Guangyu, Kou, Zhihua, Ma, Cuiqing, Sun, Shihui, Poon, Vincent K M, Lu, Lu, Wang, Lili, Debnath, Asim K, Zheng, Bo-Jian, Zhou, Yusen, Jiang, Shibo
• Format: Article
• Language: English
• Subjects: Animals; Antibodies; Antibodies, Neutralizing - blood; Antibodies, Viral - blood; Binding Sites; Cell Line; Coronavirus - genetics; Coronavirus - immunology; Coronavirus - metabolism; Coronavirus Infections - virology; Dipeptidyl Peptidase 4 - metabolism; Humans; Mice; Mice, Inbred BALB C; Protein Structure, Tertiary; Receptors, Virus - metabolism; Respiratory Tract Infections - virology; SARS coronavirus; Spike Glycoprotein, Coronavirus - genetics; Spike Glycoprotein, Coronavirus - immunology; Spike Glycoprotein, Coronavirus - metabolism; Viral Vaccines - genetics; Viral Vaccines - immunology; Virus-Cell Interactions
• ISSN: 0022-538X; 1098-5514
• DOI: 10.1128/JVI.01048-13

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