Endoscopic third ventriculocisternostomy in hydrocephalic children under 2 years of age: appropriate or not? A single-center retrospective cohort study

• Published in: Child's nervous system 2013-03, Vol.29 (3), p.419-423
• Main Authors: Fani, L., de Jong, T. H. R., Dammers, R., van Veelen, M. L. C.
• Format: Article
• Language: English
• Subjects: Age Factors; Child, Preschool; Cohort Studies; Endoscopy - methods; Female; Humans; Hydrocephalus - surgery; Infant; Male; Medicine; Medicine & Public Health; Neurosciences; Neurosurgery; Original Paper; Retrospective Studies; Third Ventricle - pathology; Third Ventricle - surgery; Ventriculostomy - instrumentation; Ventriculostomy - methods
• ISSN: 0256-7040; 1433-0350
• DOI: 10.1007/s00381-012-1961-z

Purpose Treating hydrocephalus can be difficult in children under the age of 2 years because a high amount of uncertainty exists as to which treatment to perform. In this retrospective cohort study, we analyzed children under the age of 2 years with hydrocephalus undergoing an endoscopic third ventriculocisternostomy (ETV) with respect to ETV outcome. Methods In 59 consecutive patients under the age of 2 years, an ETV was performed between 1999 and 2010 at the Erasmus MC, Sophia Children’s Hospital. Demographics, etiology of hydrocephalus, and radiological data were extracted retrospectively from the patients’ medical records and operative reports and related to outcome. ETV Success Score (ETVSS) was used to retrospectively calculate the probability of success related to the actual outcome. Results In this series, 42.4 % of patients had a successful ETV. The only statistically significant finding concerned age. The failed ETV patients appeared to be younger (0.52 ± 0.60 vs. 0.86 ± 0.56 year, p  = 0.005), and when using a cutoff age of 6 months only, five out of 32 infants had a successful ETV ( p  = 0.002). Of the children with an arachnoid cyst, 57.1 % were treated successfully with an ETV. Of the five patients with a high probability of ETV success, four (80 %) were indeed successfully treated with ETV ( p  = 0.049). Conclusions Our data confirm the overall ineffectiveness of an ETV in children under the age of 6 months. Nevertheless, using the ETVSS is recommended to aid in the decision-making process even in patients under the age of 6 months.