Nationwide study of the susceptibility of the Bacteroides fagilis group in the United States

A nationwide susceptibility survey of the B. fragilis group was continued at New England Medical Center in 1983. A total of 555 strains were obtained from eight centers in the United States. In addition to the nine antimicrobial agents studied in the two previous years, three other agents were added...

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Bibliographic Details
Published in:Antimicrobial agents and chemotherapy 1985-01, Vol.28 (5), p.675-677
Main Authors: Tally, F P, Cuchural, GJ Jr, Jacobus, N V, Gorbach, S L, Aldridge, K, Cleary, T, Finegold, S M, Hill, G, Iannini, P
Format: Article
Language:English
Subjects:
Bacteroides fragilis
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Summary:A nationwide susceptibility survey of the B. fragilis group was continued at New England Medical Center in 1983. A total of 555 strains were obtained from eight centers in the United States. In addition to the nine antimicrobial agents studied in the two previous years, three other agents were added to the evaluation: cefamandole, cefuroxime, and cefonicid. The results for the strains tested with the original nine drugs in 1983 were compared with those for 1,292 isolates tested in 1981 and 1982. The most active beta-lactam drug was piperacillin, which had an 8% resistance rate. Cefoxitin resistance increased from 10% in 1982 to 16% in 1983. High rates of resistance to cefotaxime, cefoperazone, cefamandole, cefonicid, and cefuroxime were encountered. These data indicate the need for determining the susceptibility patterns for the B. fragilis group of organisms at each hospital.
ISSN:0066-4804