Ultrasensitive chemiluminescent immunoassay labeled with graphene oxide

Graphene oxide (GO) was for the first time designed as a bionanolabel for sensitive chemiluminescent (CL) immunosensing of human IgG by taking advantage of a magnetic separation-mixing process and a GO-triggered luminol-H sub(2)O sub(2) CL reaction. The detection limit of the concentration of human...

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Bibliographic Details
Published in:Analytical methods 2013-01, Vol.5 (15), p.3646-3649
Main Authors: Song, Yinhuan, Yang, Taoyi, Zhang, Tonghuan, Jin, Nan, Zhao, Yanjun, Fan, Aiping
Format: Article
Language:English
Subjects:
Chemiluminescence
Graphene
Human
Immunoassay
Mathematical analysis
Oxides
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Summary:Graphene oxide (GO) was for the first time designed as a bionanolabel for sensitive chemiluminescent (CL) immunosensing of human IgG by taking advantage of a magnetic separation-mixing process and a GO-triggered luminol-H sub(2)O sub(2) CL reaction. The detection limit of the concentration of human IgG is 1.2 pg mL super(-1), which is comparable with or better than other immunoassays.
ISSN:1759-9660
1759-9679
DOI:10.1039/c3ay40737c