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Subclinical thyroid disease
Subclinical thyroid disease is a common finding on testing of thyroid function and its management remains controversial. Epidemiological data from large population studies from USA and Europe. There is an increased risk of progression to overt hypothyroidism or hyperthyroidism. The treatment of mild...
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| Published in: | British medical bulletin 2013-09, Vol.107 (1), p.101-116 |
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| Main Authors: | , |
| Format: | Article |
| Language: | English |
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| cites | cdi_FETCH-LOGICAL-c323t-66ec6fc5c58da0603890e368f189f6996c059482d1bdda597f2e4efc9b52fe4a3 |
| container_end_page | 116 |
| container_issue | 1 |
| container_start_page | 101 |
| container_title | British medical bulletin |
| container_volume | 107 |
| creator | Garg, Anukul Vanderpump, Mark P J |
| description | Subclinical thyroid disease is a common finding on testing of thyroid function and its management remains controversial.
Epidemiological data from large population studies from USA and Europe.
There is an increased risk of progression to overt hypothyroidism or hyperthyroidism. The treatment of mild thyroid failure is of importance in optimizing pregnancy outcome.
Diagnostic criteria differ and there is variation between management guidelines. The difference was found in long-term clinical outcomes between endogenous and exogenous subclinical hyperthyroidism.
Meta-analyses have provided epidemiological data in cardiovascular mortality and morbidity in subclinical thyroid disease. Increased use of echocardiography and bone markers in identifying those who benefit from intervention.
A randomized controlled trial to identify those subjects identified from screening programmes that benefit from intervention in terms of morbidity and mortality. |
| doi_str_mv | 10.1093/bmb/ldt024 |
| format | article |
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Epidemiological data from large population studies from USA and Europe.
There is an increased risk of progression to overt hypothyroidism or hyperthyroidism. The treatment of mild thyroid failure is of importance in optimizing pregnancy outcome.
Diagnostic criteria differ and there is variation between management guidelines. The difference was found in long-term clinical outcomes between endogenous and exogenous subclinical hyperthyroidism.
Meta-analyses have provided epidemiological data in cardiovascular mortality and morbidity in subclinical thyroid disease. Increased use of echocardiography and bone markers in identifying those who benefit from intervention.
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Epidemiological data from large population studies from USA and Europe.
There is an increased risk of progression to overt hypothyroidism or hyperthyroidism. The treatment of mild thyroid failure is of importance in optimizing pregnancy outcome.
Diagnostic criteria differ and there is variation between management guidelines. The difference was found in long-term clinical outcomes between endogenous and exogenous subclinical hyperthyroidism.
Meta-analyses have provided epidemiological data in cardiovascular mortality and morbidity in subclinical thyroid disease. Increased use of echocardiography and bone markers in identifying those who benefit from intervention.
A randomized controlled trial to identify those subjects identified from screening programmes that benefit from intervention in terms of morbidity and mortality.</description><subject>Female</subject><subject>Humans</subject><subject>Hyperthyroidism - diagnosis</subject><subject>Hyperthyroidism - drug therapy</subject><subject>Hyperthyroidism - etiology</subject><subject>Hypothyroidism - diagnosis</subject><subject>Hypothyroidism - drug therapy</subject><subject>Hypothyroidism - etiology</subject><subject>Male</subject><subject>Pregnancy</subject><subject>Pregnancy Complications - diagnosis</subject><subject>Pregnancy Complications - drug therapy</subject><subject>Pregnancy Complications - epidemiology</subject><subject>Thyroid Diseases - diagnosis</subject><subject>Thyroid Diseases - epidemiology</subject><subject>Thyroid Gland - physiopathology</subject><subject>Thyroiditis, Autoimmune</subject><issn>0007-1420</issn><issn>1471-8391</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNo9kEtLw0AUhQdRbKxu3ArSpQixdx6ZzCyl-IKCC3U9zOMORpKmziSL_nsjra7O4nwcOB8hlxTuKGi-dJ1btmEAJo5IQUVNS8U1PSYFANQlFQxm5CznLwDKOahTMmNTr3VFC3L1NjrfNpvG23YxfO5S34RFaDLajOfkJNo248Uh5-Tj8eF99VyuX59eVvfr0nPGh1JK9DL6ylcqWJDAlQbkUkWqdJRaSw-VFooF6kKwla4jQ4HRa1exiMLyObnZ725T_z1iHkzXZI9tazfYj9lQwYFrNR2b0Ns96lOfc8JotqnpbNoZCuZXhplkmL2MCb4-7I6uw_CP_r3nP6UGWbU</recordid><startdate>20130901</startdate><enddate>20130901</enddate><creator>Garg, Anukul</creator><creator>Vanderpump, Mark P J</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20130901</creationdate><title>Subclinical thyroid disease</title><author>Garg, Anukul ; Vanderpump, Mark P J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c323t-66ec6fc5c58da0603890e368f189f6996c059482d1bdda597f2e4efc9b52fe4a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Female</topic><topic>Humans</topic><topic>Hyperthyroidism - diagnosis</topic><topic>Hyperthyroidism - drug therapy</topic><topic>Hyperthyroidism - etiology</topic><topic>Hypothyroidism - diagnosis</topic><topic>Hypothyroidism - drug therapy</topic><topic>Hypothyroidism - etiology</topic><topic>Male</topic><topic>Pregnancy</topic><topic>Pregnancy Complications - diagnosis</topic><topic>Pregnancy Complications - drug therapy</topic><topic>Pregnancy Complications - epidemiology</topic><topic>Thyroid Diseases - diagnosis</topic><topic>Thyroid Diseases - epidemiology</topic><topic>Thyroid Gland - physiopathology</topic><topic>Thyroiditis, Autoimmune</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Garg, Anukul</creatorcontrib><creatorcontrib>Vanderpump, Mark P J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>British medical bulletin</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Garg, Anukul</au><au>Vanderpump, Mark P J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Subclinical thyroid disease</atitle><jtitle>British medical bulletin</jtitle><addtitle>Br Med Bull</addtitle><date>2013-09-01</date><risdate>2013</risdate><volume>107</volume><issue>1</issue><spage>101</spage><epage>116</epage><pages>101-116</pages><issn>0007-1420</issn><eissn>1471-8391</eissn><abstract>Subclinical thyroid disease is a common finding on testing of thyroid function and its management remains controversial.
Epidemiological data from large population studies from USA and Europe.
There is an increased risk of progression to overt hypothyroidism or hyperthyroidism. The treatment of mild thyroid failure is of importance in optimizing pregnancy outcome.
Diagnostic criteria differ and there is variation between management guidelines. The difference was found in long-term clinical outcomes between endogenous and exogenous subclinical hyperthyroidism.
Meta-analyses have provided epidemiological data in cardiovascular mortality and morbidity in subclinical thyroid disease. Increased use of echocardiography and bone markers in identifying those who benefit from intervention.
A randomized controlled trial to identify those subjects identified from screening programmes that benefit from intervention in terms of morbidity and mortality.</abstract><cop>England</cop><pmid>23919951</pmid><doi>10.1093/bmb/ldt024</doi><tpages>16</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0007-1420 |
| ispartof | British medical bulletin, 2013-09, Vol.107 (1), p.101-116 |
| issn | 0007-1420 1471-8391 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1430398471 |
| source | Oxford Journals Online |
| subjects | Female Humans Hyperthyroidism - diagnosis Hyperthyroidism - drug therapy Hyperthyroidism - etiology Hypothyroidism - diagnosis Hypothyroidism - drug therapy Hypothyroidism - etiology Male Pregnancy Pregnancy Complications - diagnosis Pregnancy Complications - drug therapy Pregnancy Complications - epidemiology Thyroid Diseases - diagnosis Thyroid Diseases - epidemiology Thyroid Gland - physiopathology Thyroiditis, Autoimmune |
| title | Subclinical thyroid disease |
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