Management and recurrence of keratocystic odontogenic tumor: a systematic review

Objectives The objective of this study was to evaluate the most up-to-date treatment modalities and respective recurrence rates for keratocystic odontogenic tumor (KCOT). Study Design A systematic review of the literature from 1999 to 2010 was undertaken examining treatment and recurrence rates for...

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Published in:Oral surgery, oral medicine, oral pathology and oral radiology oral medicine, oral pathology and oral radiology, 2013-10, Vol.116 (4), p.e271-e276
Main Authors: Johnson, Nigel R., BDSc (Hons), MBBS, Batstone, Martin D., MBBS, BDSc (Hons), MPhil (Surg), FRACDS (OMS), FRCS (OMFS), Savage, Neil W., MDSc, PhD, FFOP (RCPA), FICD
Format: Article
Language:English
Subjects:
Acetic Acid - therapeutic use
Chloroform - therapeutic use
Dentistry
Ethanol - therapeutic use
Humans
Jaw Neoplasms - pathology
Jaw Neoplasms - surgery
Neoplasm Recurrence, Local
Odontogenic Cysts - pathology
Odontogenic Cysts - surgery
Odontogenic Tumors - pathology
Odontogenic Tumors - surgery
Oral Surgical Procedures - methods
Surgery
Treatment Outcome
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Summary:Objectives The objective of this study was to evaluate the most up-to-date treatment modalities and respective recurrence rates for keratocystic odontogenic tumor (KCOT). Study Design A systematic review of the literature from 1999 to 2010 was undertaken examining treatment and recurrence rates for KCOT. Four inclusion criteria were defined for articles to then be analyzed against 8 standards. Results Of the 2736 published articles, 8 met the inclusion criteria. When merging the data, enucleation and enucleation with adjunctive measures (other than Carnoy's solution) had recurrence rates of 25.6% and 30.3%, respectively. Marsupialization with adjunctive measures produced a recurrence rate of 15.8%, whereas enucleation with Carnoy's solution presented a recurrence rate of 7.9%. Only one resection case had recurrence (6.3%). Conclusions The enucleation technique with the use of adjunctive procedures (other than Carnoy's solution) provides a higher recurrence rate than any other treatment modality.
ISSN:2212-4403
2212-4411
DOI:10.1016/j.oooo.2011.12.028