Consequences of prematurity on adult morbidities

Abstract Early life events play a key role in the development of adult diseases. Survival is promoted by the developmental adaptation to environment although advantage in the short term implies a long-term cost with regard to the development of adult morbidities. This is particularly true for the in...

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Bibliographic Details
Published in:European journal of internal medicine 2013-10, Vol.24 (7), p.624-626
Main Authors: Roggero, P, Giannì, M.L, Garbarino, F, Mosca, F
Format: Article
Language:English
Subjects:
Adult
Cardiovascular Diseases - epidemiology
Corneal Dystrophies, Hereditary
Humans
Infant, Newborn
Infant, Premature - growth & development
Internal Medicine
Kidney Diseases - epidemiology
Long term health
Lung Diseases - epidemiology
Metabolic Diseases - epidemiology
Morbidity
Prematurity
Programming
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Summary:Abstract Early life events play a key role in the development of adult diseases. Survival is promoted by the developmental adaptation to environment although advantage in the short term implies a long-term cost with regard to the development of adult morbidities. This is particularly true for the infant born prematurely as preterm birth is accompanied by a disruption of the normal organogenesis of multiple organ systems. This review will examine the effect of prematurity on the development of cardiovascular, kidney, respiratory and metabolic diseases in later life in addition to the neurodevelopment disabilities associated with preterm birth.
ISSN:0953-6205
1879-0828
DOI:10.1016/j.ejim.2013.01.011