Optimizing the role of FDG PET–CT for potentially operable metastatic colorectal cancer

Recent treatment advances now allow a realistic chance of cure in selected patients with metastatic colorectal carcinoma (CRC). Accurate pre-treatment staging is crucial to ensure appropriate management by identification of patients with more advanced disease who will not benefit from surgery. 18 Fl...

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Bibliographic Details
Published in:Abdominal imaging 2012-12, Vol.37 (6), p.1021-1031
Main Authors: Culverwell, A. D., Chowdhury, F. U., Scarsbrook, A. F.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Carcinoembryonic Antigen - blood
Colonography, Computed Tomographic
Colorectal cancer
Colorectal Neoplasms - diagnostic imaging
Colorectal Neoplasms - pathology
Colorectal Neoplasms - surgery
Cost-Benefit Analysis
Fluorodeoxyglucose F18
Gastroenterology
Gastroenterology. Liver. Pancreas. Abdomen
Hepatology
Humans
Imaging
Liver Neoplasms - secondary
Medical sciences
Medicine
Medicine & Public Health
Multimodal Imaging - economics
Neoplasm Invasiveness
Neoplasm Recurrence, Local - diagnosis
Neoplasm Staging
Positron-Emission Tomography
Radiology
Radiopharmaceuticals
Sensitivity and Specificity
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
Tomography, X-Ray Computed
Tumors
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Summary:Recent treatment advances now allow a realistic chance of cure in selected patients with metastatic colorectal carcinoma (CRC). Accurate pre-treatment staging is crucial to ensure appropriate management by identification of patients with more advanced disease who will not benefit from surgery. 18 Fluorine 2-fluoro-2-deoxy- d -glucose positron emission tomography–computed tomography (PET–CT) has a firmly established role in staging, restaging, and recurrence detection of a range of tumors. This article will review the role of PET–CT in patients with CRC with a particular emphasis on optimizing the technique in patients with potentially operable metastatic disease.
ISSN:0942-8925
2366-004X
1432-0509
2366-0058
DOI:10.1007/s00261-012-9855-9