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Clinical target volume delineation for radiotherapy of the esophagus

The dense lymphatic network of the esophagus facilitates tumour spreading along the cephalo-caudal axis and to locoregional lymph nodes. A better understanding of microscopic invasion by tumour cells, based on histological analysis of surgical specimens and analysis of recurrence sites, has justifie...

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Bibliographic Details
Published in:Cancer radiothérapie 2013-10, Vol.17 (5-6), p.453-460
Main Authors: Lazarescu, I, Thureau, S, Nkhali, L, Pradier, O, Dubray, B
Format: Article
Language:fre
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Summary:The dense lymphatic network of the esophagus facilitates tumour spreading along the cephalo-caudal axis and to locoregional lymph nodes. A better understanding of microscopic invasion by tumour cells, based on histological analysis of surgical specimens and analysis of recurrence sites, has justified a reduction in radiotherapy target volumes. The delineation of the clinical target volume (CTV) depends on tumour characteristics (site, histology) and on its spread as assessed on endoscopic ultrasonography and ((18)F)-fluorodeoxyglucose positron-emission tomography (FDG-PET). We propose that positive and negative predictive values for FDG-PET should be used to adapt the CTV according to the risk of nodal involvement.
ISSN:1769-6658
DOI:10.1016/j.canrad.2013.07.145