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Clinical target volume delineation for radiotherapy of the esophagus
The dense lymphatic network of the esophagus facilitates tumour spreading along the cephalo-caudal axis and to locoregional lymph nodes. A better understanding of microscopic invasion by tumour cells, based on histological analysis of surgical specimens and analysis of recurrence sites, has justifie...
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Published in: | Cancer radiothérapie 2013-10, Vol.17 (5-6), p.453-460 |
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Main Authors: | , , , , |
Format: | Article |
Language: | fre |
Subjects: | |
Online Access: | Get full text |
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Summary: | The dense lymphatic network of the esophagus facilitates tumour spreading along the cephalo-caudal axis and to locoregional lymph nodes. A better understanding of microscopic invasion by tumour cells, based on histological analysis of surgical specimens and analysis of recurrence sites, has justified a reduction in radiotherapy target volumes. The delineation of the clinical target volume (CTV) depends on tumour characteristics (site, histology) and on its spread as assessed on endoscopic ultrasonography and ((18)F)-fluorodeoxyglucose positron-emission tomography (FDG-PET). We propose that positive and negative predictive values for FDG-PET should be used to adapt the CTV according to the risk of nodal involvement. |
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ISSN: | 1769-6658 |
DOI: | 10.1016/j.canrad.2013.07.145 |