Population-Based Study of Disability and Institutionalization After Transient Ischemic Attack and Stroke: 10-Year Results of the Oxford Vascular Study

Long-term outcome information after transient ischemic attack (TIA) and stroke is required to help plan and allocate care services. We evaluated the impact of TIA and stroke on disability and institutionalization over 5 years using data from a population-based study. Patients from a UK population-ba...

Full description

Saved in:
Bibliographic Details
Published in:Stroke (1970) 2013-10, Vol.44 (10), p.2854-2861
Main Authors: Luengo-Fernandez, Ramon, Paul, Nicola L.M., Gray, Alastair M., Pendlebury, Sarah T., Bull, Linda M., Welch, Sarah J.V., Cuthbertson, Fiona C., Rothwell, Peter M.
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Biological and medical sciences
Blood. Blood coagulation. Reticuloendothelial system
Brain Ischemia - mortality
Brain Ischemia - therapy
Disability Evaluation
Disease-Free Survival
England - epidemiology
Female
Follow-Up Studies
Hospitalization
Humans
Male
Medical sciences
Middle Aged
Neurology
Pharmacology. Drug treatments
Risk Factors
Stroke - mortality
Stroke - therapy
Survival Rate
Time Factors
Vascular diseases and vascular malformations of the nervous system
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Long-term outcome information after transient ischemic attack (TIA) and stroke is required to help plan and allocate care services. We evaluated the impact of TIA and stroke on disability and institutionalization over 5 years using data from a population-based study. Patients from a UK population-based cohort study (Oxford Vascular Study) were recruited from 2002 to 2007 and followed up to 2012. Patients were followed up at 1, 6, 12, 24, and 60 months postevent and assessed using the modified Rankin scale. A multivariate regression analysis was performed to assess the predictors of disability postevent. A total of 748 index stroke and 440 TIA cases were studied. For patients with TIA, disability levels increased from 14% (63 of 440) premorbidly to 23% (60 of 256) at 5 years (P=0.002), with occurrence of subsequent stroke being a major predictor of disability. For stroke survivors, the proportion disabled (modified Rankin scale >2) increased from 21% (154 of 748) premorbidly to 43% (273 of 634) at 1 month (P
ISSN:0039-2499
1524-4628
DOI:10.1161/STROKEAHA.113.001584