Copper-Catalyzed B–H Bond Insertion Reaction: A Highly Efficient and Enantioselective C–B Bond-Forming Reaction with Amine–Borane and Phosphine–Borane Adducts

A copper-catalyzed B–H bond insertion reaction with amine– and phosphine–borane adducts was realized with high yield and enantioselectivity under mild reaction conditions. The B–H bond insertion reaction provides a new C–B bond-forming methodology and an efficient approach to chiral organoboron comp...

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Bibliographic Details
Published in:Journal of the American Chemical Society 2013-09, Vol.135 (38), p.14094-14097
Main Authors: Cheng, Qing-Qing, Zhu, Shou-Fei, Zhang, Yong-Zhen, Xie, Xiu-Lan, Zhou, Qi-Lin
Format: Article
Language:English
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Summary:A copper-catalyzed B–H bond insertion reaction with amine– and phosphine–borane adducts was realized with high yield and enantioselectivity under mild reaction conditions. The B–H bond insertion reaction provides a new C–B bond-forming methodology and an efficient approach to chiral organoboron compounds.
ISSN:0002-7863
1520-5126
DOI:10.1021/ja408306a