No indication of mutagenicity by ofloxacin

There was no significant harmful effect on the DNA of eukaryotes. Ofloxacin did not cause any point mutations, nor did it induce any in vivo or in vitro chromosome mutation in the systems tested. These tests lead to the conclusion that there are no indications of ofloxacin having any mutagenic effec...

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Bibliographic Details
Main Authors: Mayer, D, Bruch, K
Format: Book Chapter
Language:ger
Online Access:Get full text
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Summary:There was no significant harmful effect on the DNA of eukaryotes. Ofloxacin did not cause any point mutations, nor did it induce any in vivo or in vitro chromosome mutation in the systems tested. These tests lead to the conclusion that there are no indications of ofloxacin having any mutagenic effects.
ISSN:0300-8126