Single-Chain Fragmented Antibodies Guided SiRNA Delivery in Breast Cancer

Over the past ten years, the enthusiasm to harness small RNA molecules, mainly small interfering RNAs （siRNAs） and microRNA mimics, into therapeutic weapons has never been quenched. However, a major obstacle hindering the clinical application of these small molecules is how to efficiently and precis...

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Bibliographic Details
Published in:Science foundation in China 2012, Vol.20 (1), p.24-24
Main Authors: Wei, H, Cui, L, Erdan, D
Format: Article
Language:English
Subjects:
Antibodies
microRNA
siRNAs
乳腺癌
传递
分散
单链抗体
小RNA
小分子干扰RNA
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Summary:Over the past ten years, the enthusiasm to harness small RNA molecules, mainly small interfering RNAs （siRNAs） and microRNA mimics, into therapeutic weapons has never been quenched. However, a major obstacle hindering the clinical application of these small molecules is how to efficiently and precisely deliver siRNAs in vivo into target cells to silence target genes.
ISSN:1005-0841