Space Research Program on Planarian Schmidtea Mediterranea’s Establishment of the Anterior-Posterior Axis in Altered Gravity Conditions

Planarians of the species Schmidtea mediterranea are a well-established model for regeneration studies. In this paper, we first recall the morphological characters and the molecular mechanisms involved in the regeneration process, especially focussing on the Wnt pathway and the establishment of the...

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Bibliographic Details
Published in:Microgravity science and technology 2012-12, Vol.24 (6), p.419-425
Main Authors: Auletta, G., Adell, T., Colagè, I., D’Ambrosio, P., Salò, E.
Format: Article
Language:English
Subjects:
Aerospace Technology and Astronautics
Assessments
Classical and Continuum Physics
Engineering
Genetics
Gravitation
Microgravity
Original Article
Polarity
Recall
Regeneration
Segments
Space Exploration and Astronautics
Space Sciences (including Extraterrestrial Physics
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Summary:Planarians of the species Schmidtea mediterranea are a well-established model for regeneration studies. In this paper, we first recall the morphological characters and the molecular mechanisms involved in the regeneration process, especially focussing on the Wnt pathway and the establishment of the antero-posterior axial polarity. Then, after an assessment of a space-experiment (run in 2006 on the Russian Segment of the International Space Station) on planarians of the species Girardia tigrina , we present our experimental program to ascertain the effects that altered-gravity conditions may have on regeneration processes in S. mediterrnea at the molecular and genetic level.
ISSN:0938-0108
1875-0494
DOI:10.1007/s12217-012-9317-6