Self-Assembly: A Robust Route to Enzymatically Functional, Hierarchically Self-Assembled Peptide Frameworks (Adv. Mater. 19/2013)

Adding enzyme biofunctionality to peptide nanofibers is challenging since this can inhibit enzyme activity and peptide self-assembly. Easan Sivaniah and co-workers demonstrate the attachment of a polymerization synthase to peptide nanofibers via a selective non-covalent peptide tag. The biofunctiona...

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Bibliographic Details
Published in:Advanced materials (Weinheim) 2013-05, Vol.25 (19), p.2633-2633
Main Authors: Sangiambut, S., Channon, K., Thomson, N. M., Sato, S., Tsuge, T., Doi, Y., Sivaniah, E.
Format: Article
Language:English
Subjects:
Attachment
Biocompatibility
Coating
enzymatically functional materials
Enzymes
hierarchical self-assembly
in-vitro biopolyester synthesis
Nanofibers
peptide frameworks
Peptides
Polymerization
Self assembly
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Summary:Adding enzyme biofunctionality to peptide nanofibers is challenging since this can inhibit enzyme activity and peptide self-assembly. Easan Sivaniah and co-workers demonstrate the attachment of a polymerization synthase to peptide nanofibers via a selective non-covalent peptide tag. The biofunctionalization, rapidly achieved, generates a biocompatible biopolyester coat on the fibers, with applicability in biomedical engineering. Cover image by Effigos AG.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.201370121