Electrolyte-Gated Organic Field-Effect Transistor Sensors Based on Supported Biotinylated Phospholipid Bilayer

Anchored, biotinylated phospholipids forming the capturing layers in an electrolyte‐gated organic field‐effect transistor (EGOFET) allow label‐free electronic specific detection at a concentration level of 10 nM in a high ionic strength solution. The sensing mechanism is based on a clear capacitive...

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Bibliographic Details
Published in:Advanced materials (Weinheim) 2013-04, Vol.25 (14), p.2090-2094
Main Authors: Magliulo, Maria, Mallardi, Antonia, Mulla, Mohammad Yusuf, Cotrone, Serafina, Pistillo, Bianca Rita, Favia, Pietro, Vikholm-Lundin, Inger, Palazzo, Gerardo, Torsi, Luisa
Format: Article
Language:English
Subjects:
Avidin - chemistry
Avidin - metabolism
Biosensing Techniques
Biotin - chemistry
Biotin - metabolism
Biotinylation
Detection
electrolyte-gated organic field-effect transistors
Electrolytes - chemistry
electronic sensing
Electronics
Forming
organic field-effect transistors
Osmolar Concentration
Phospholipids
Phospholipids - chemistry
Semiconductor devices
Sensors
Strength
Transistors
Transistors, Electronic
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Summary:Anchored, biotinylated phospholipids forming the capturing layers in an electrolyte‐gated organic field‐effect transistor (EGOFET) allow label‐free electronic specific detection at a concentration level of 10 nM in a high ionic strength solution. The sensing mechanism is based on a clear capacitive effect across the PL layers involving the charges of the target molecules.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.201203587