Continuous separation of colloidal particles using dielectrophoresis

Dielectrophoresis is the movement of particles in nonuniform electric fields and has been of interest for application to manipulation and separation at and below the microscale. This technique has the advantages of being noninvasive, nondestructive, and noncontact, with the movement of particle achi...

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Bibliographic Details
Published in:Electrophoresis 2013-04, Vol.34 (7), p.969-978
Main Authors: Yunus, Nurul Amziah Md, Nili, Hossein, Green, Nicolas G.
Format: Article
Language:English
Subjects:
Arrays
Colloidal
Colloids
Colloids - chemistry
Colloids - isolation & purification
Dielectrophoresis
Electric fields
Electrophoresis - instrumentation
Electrophoresis - methods
Image Processing, Computer-Assisted
Microelectrodes
Microfluidic Analytical Techniques - instrumentation
Microfluidic Analytical Techniques - methods
Microfluidics
Microspheres
Movement
Nanoparticles - chemistry
Nanostructure
Separation
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Summary:Dielectrophoresis is the movement of particles in nonuniform electric fields and has been of interest for application to manipulation and separation at and below the microscale. This technique has the advantages of being noninvasive, nondestructive, and noncontact, with the movement of particle achieved by means of electric fields generated by miniaturized electrodes and microfluidic systems. Although the majority of applications have been above the microscale, there is increasing interest in application to colloidal particles around a micron and smaller. This paper begins with a review of colloidal and nanoscale dielectrophoresis with specific attention paid to separation applications. An innovative design of integrated microelectrode array and its application to flow‐through, continuous separation of colloidal particles is then presented. The details of the angled chevron microelectrode array and the test microfluidic system are then discussed. The variation in device operation with applied signal voltage is presented and discussed in terms of separation efficiency, demonstrating 99.9% separation of a mixture of colloidal latex spheres.
ISSN:0173-0835
1522-2683
DOI:10.1002/elps.201200466