Studies on the structure-property relationship of sodium alginate based thixotropic hydrogels

Sodium alginate (Na-Alg) reacted with 1-naphthylamine in the presence of 1-ethyl-3-[3-(dimethylamino)propyl]-carbodiimide hydrochloride (EDC·HCl) affording an amide derivative capable of forming soft hydrogel at a concentration of 4% w/v. The latter upon gentle stirring turned into a viscous sol, wh...

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Bibliographic Details
Published in:RSC advances 2013-01, Vol.3 (36), p.15744-15751
Main Authors: Chejara, Dharmesh R, Kondaveeti, Stalin, Prasad, Kamalesh, Siddhanta, A. K
Format: Article
Language:English
Subjects:
Amides
Biomedical materials
Derivatives
Forming
Hydrogels
Sensors
Sodium alginate
Stirring
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Summary:Sodium alginate (Na-Alg) reacted with 1-naphthylamine in the presence of 1-ethyl-3-[3-(dimethylamino)propyl]-carbodiimide hydrochloride (EDC·HCl) affording an amide derivative capable of forming soft hydrogel at a concentration of 4% w/v. The latter upon gentle stirring turned into a viscous sol, which assumed the original gel structure upon standing at room temperature in a reversible process. Such thixotropic materials have the potential to be used in biomedical applications and as sensors. Structure-thixotropic property relationship of sodium alginate based amides of 1-naphthylamine, 2-amino anthracene and aniline were studied.
ISSN:2046-2069
2046-2069
DOI:10.1039/c3ra43070g