Epidemiology of Hepatitis C Virus Infection and Risk Factor Analysis in the Hebei Province, China: e75586

Background In 1985, a hepatitis C virus (HCV) outbreak caused by plasmapheresis donation was reported in the Hebei Province, China. However, studies assessing the epidemic features and risk factors of HCV in the general population of Hebei have been limited until now. Methods The multicenter cluster...

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Bibliographic Details
Published in:PloS one 2013-09, Vol.8 (9)
Main Authors: Zhao, Yuliang, Shen, Liping, Ma, Jingchen, Gao, Zhao, Han, Xu, Qi, Shunxiang, Li, Qi
Format: Article
Language:English
Subjects:
Age
Hepatitis C virus
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Summary:Background In 1985, a hepatitis C virus (HCV) outbreak caused by plasmapheresis donation was reported in the Hebei Province, China. However, studies assessing the epidemic features and risk factors of HCV in the general population of Hebei have been limited until now. Methods The multicenter cluster sampling method was used to collect samples. The participants were interviewed. Relevant information was obtained from the general population using a standardized questionnaire, and association and logistic regression analyses were conducted. Serum samples were taken to test anti-HCV by enzyme immunoassays. Results A total of 4562 participants from 11 cities of the Hebei Province were enrolled. The average anti-HCV positive rate was 0.62% (29/4562), which was 1.07% in the rural population, compared with 0.22% in the urban population. The anti-HCV positive rate in the 40-59-year age group was higher than in those aged
ISSN:1932-6203
DOI:10.1371/journal.pone.0075586