Neurexophilin 1 Gene Polymorphism in Chickens and Its Variation Among Species

Neurexophilin 1 (nxph1) has been considered a potential candidate marker for sperm storage in chicken sperm storage tubules. In this work, one mutation of chicken nxph1 was detected. We analyzed 18 nxph1 gene sequences from 18 species. The coding sequence length of the zebra fish nxph1 gene is 819 b...

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Published in:Biochemical genetics 2013-08, Vol.51 (7-8), p.618-625
Main Authors: Liu, Guiqiong, Jiang, Xunping, He, Chunbo, Tang, Zhou
Format: Article
Language:English
Subjects:
Alleles
Amino Acid Sequence
Amino acids
Animals
Base Sequence
Biochemistry
Biomedical and Life Sciences
Biomedicine
Chickens
Chickens - genetics
Codon
Danio rerio
evolution
genes
genetic polymorphism
Glycoproteins - genetics
Human Genetics
Mammals
Medical Microbiology
Molecular Sequence Data
Mutation
Neuropeptides - genetics
nucleotide sequences
Phylogeny
Polymorphism, Genetic
Sequence Alignment
Sequence Homology, Amino Acid
Species Specificity
spermatozoa
Zoology
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creator Liu, Guiqiong
Jiang, Xunping
He, Chunbo
Tang, Zhou
description Neurexophilin 1 (nxph1) has been considered a potential candidate marker for sperm storage in chicken sperm storage tubules. In this work, one mutation of chicken nxph1 was detected. We analyzed 18 nxph1 gene sequences from 18 species. The coding sequence length of the zebra fish nxph1 gene is 819 bp; that of the other species is 816 bp. Amino acid alignment analysis revealed that the gene product is a conserved protein, especially in mammals. The sequences of mammals are highly conserved. We found 202 conserved amino acids (70–271), and there were only eight mutations in the remaining 69 amino acids. That level of conservation could be due to the nxph1 gene having been subjected to substantial constraints or strong purifying selection during millions of years of evolution.
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In this work, one mutation of chicken nxph1 was detected. We analyzed 18 nxph1 gene sequences from 18 species. The coding sequence length of the zebra fish nxph1 gene is 819 bp; that of the other species is 816 bp. Amino acid alignment analysis revealed that the gene product is a conserved protein, especially in mammals. The sequences of mammals are highly conserved. We found 202 conserved amino acids (70–271), and there were only eight mutations in the remaining 69 amino acids. 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1573-4927
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source Springer Nature
subjects Alleles
Amino Acid Sequence
Amino acids
Animals
Base Sequence
Biochemistry
Biomedical and Life Sciences
Biomedicine
Chickens
Chickens - genetics
Codon
Danio rerio
evolution
genes
genetic polymorphism
Glycoproteins - genetics
Human Genetics
Mammals
Medical Microbiology
Molecular Sequence Data
Mutation
Neuropeptides - genetics
nucleotide sequences
Phylogeny
Polymorphism, Genetic
Sequence Alignment
Sequence Homology, Amino Acid
Species Specificity
spermatozoa
Zoology
title Neurexophilin 1 Gene Polymorphism in Chickens and Its Variation Among Species
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