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Relationship between knee alignment and T1ρ values of articular cartilage and menisci in patients with knee osteoarthritis
To assess the relationship between knee alignment and subregional T1ρ values of the femorotibial cartilage and menisci in patients with mild (Kellgren–Lawrence grade 1) to moderate (KL3) osteoarthritis (OA) at 3T. 26 subjects with a clinical diagnosis of KL1-3 OA were included and subdivided into th...
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Published in: | European journal of radiology 2013-11, Vol.82 (11), p.1946-1952 |
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container_end_page | 1952 |
container_issue | 11 |
container_start_page | 1946 |
container_title | European journal of radiology |
container_volume | 82 |
creator | Wang, Ligong Vieira, Renata La Rocca Rybak, Leon D. Babb, James S. Chang, Gregory Krasnokutsky, Svetlana Abramson, Steven Regatte, Ravinder |
description | To assess the relationship between knee alignment and subregional T1ρ values of the femorotibial cartilage and menisci in patients with mild (Kellgren–Lawrence grade 1) to moderate (KL3) osteoarthritis (OA) at 3T.
26 subjects with a clinical diagnosis of KL1-3 OA were included and subdivided into three subgroups: varus, valgus, and neutral. All subjects were evaluated on a 3T MR scanner. Mann–Whitney and Wilcoxon signed rank tests were performed to determine any statistically significant differences in subregional T1ρ values of femorotibial cartilage and menisci among the three subgroups of KL1-3 OA patients.
Medial femoral anterior cartilage subregion in varus group had significantly higher (p |
doi_str_mv | 10.1016/j.ejrad.2013.05.010 |
format | article |
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26 subjects with a clinical diagnosis of KL1-3 OA were included and subdivided into three subgroups: varus, valgus, and neutral. All subjects were evaluated on a 3T MR scanner. Mann–Whitney and Wilcoxon signed rank tests were performed to determine any statistically significant differences in subregional T1ρ values of femorotibial cartilage and menisci among the three subgroups of KL1-3 OA patients.
Medial femoral anterior cartilage subregion in varus group had significantly higher (p<0.05) T1ρ values than all cartilage subregions in valgus group. Medial tibial central cartilage subregion had significantly higher T1ρ values (p<0.05) than lateral tibial central cartilage subregion in varus group. The posterior horn of the medial meniscus in neutral group had significantly higher T1ρ values (p<0.0029) than all meniscus subregions in valgus group.
There exists some degree of association between knee alignment and subregional T1ρ values of femorotibial cartilage and menisci in patients with clinical OA</description><identifier>ISSN: 0720-048X</identifier><identifier>EISSN: 1872-7727</identifier><identifier>DOI: 10.1016/j.ejrad.2013.05.010</identifier><identifier>PMID: 23769189</identifier><language>eng</language><publisher>Ireland: Elsevier Ireland Ltd</publisher><subject>Aged ; Algorithms ; Cartilage, Articular - pathology ; Female ; Humans ; Image Enhancement - methods ; Image Interpretation, Computer-Assisted - methods ; Knee alignment ; Knee joint ; Knee Joint - pathology ; Magnetic Resonance Imaging - methods ; Male ; Menisci, Tibial - pathology ; Meniscus ; Middle Aged ; MRI ; Osteoarthritis ; Osteoarthritis, Knee - pathology ; Reproducibility of Results ; Sensitivity and Specificity</subject><ispartof>European journal of radiology, 2013-11, Vol.82 (11), p.1946-1952</ispartof><rights>2013 Elsevier Ireland Ltd</rights><rights>Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c404t-134c5de384f8a84d07dbacf67247f45ff2e30cad61440a9d0e2d235b792539c3</citedby><cites>FETCH-LOGICAL-c404t-134c5de384f8a84d07dbacf67247f45ff2e30cad61440a9d0e2d235b792539c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23769189$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wang, Ligong</creatorcontrib><creatorcontrib>Vieira, Renata La Rocca</creatorcontrib><creatorcontrib>Rybak, Leon D.</creatorcontrib><creatorcontrib>Babb, James S.</creatorcontrib><creatorcontrib>Chang, Gregory</creatorcontrib><creatorcontrib>Krasnokutsky, Svetlana</creatorcontrib><creatorcontrib>Abramson, Steven</creatorcontrib><creatorcontrib>Regatte, Ravinder</creatorcontrib><title>Relationship between knee alignment and T1ρ values of articular cartilage and menisci in patients with knee osteoarthritis</title><title>European journal of radiology</title><addtitle>Eur J Radiol</addtitle><description>To assess the relationship between knee alignment and subregional T1ρ values of the femorotibial cartilage and menisci in patients with mild (Kellgren–Lawrence grade 1) to moderate (KL3) osteoarthritis (OA) at 3T.
26 subjects with a clinical diagnosis of KL1-3 OA were included and subdivided into three subgroups: varus, valgus, and neutral. All subjects were evaluated on a 3T MR scanner. Mann–Whitney and Wilcoxon signed rank tests were performed to determine any statistically significant differences in subregional T1ρ values of femorotibial cartilage and menisci among the three subgroups of KL1-3 OA patients.
Medial femoral anterior cartilage subregion in varus group had significantly higher (p<0.05) T1ρ values than all cartilage subregions in valgus group. Medial tibial central cartilage subregion had significantly higher T1ρ values (p<0.05) than lateral tibial central cartilage subregion in varus group. The posterior horn of the medial meniscus in neutral group had significantly higher T1ρ values (p<0.0029) than all meniscus subregions in valgus group.
There exists some degree of association between knee alignment and subregional T1ρ values of femorotibial cartilage and menisci in patients with clinical OA</description><subject>Aged</subject><subject>Algorithms</subject><subject>Cartilage, Articular - pathology</subject><subject>Female</subject><subject>Humans</subject><subject>Image Enhancement - methods</subject><subject>Image Interpretation, Computer-Assisted - methods</subject><subject>Knee alignment</subject><subject>Knee joint</subject><subject>Knee Joint - pathology</subject><subject>Magnetic Resonance Imaging - methods</subject><subject>Male</subject><subject>Menisci, Tibial - pathology</subject><subject>Meniscus</subject><subject>Middle Aged</subject><subject>MRI</subject><subject>Osteoarthritis</subject><subject>Osteoarthritis, Knee - pathology</subject><subject>Reproducibility of Results</subject><subject>Sensitivity and Specificity</subject><issn>0720-048X</issn><issn>1872-7727</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNp9kLtOHDEUhi2UCDbAE0RCLtPM5Pgy45mCIkJcIiFFQluks7z2GdabWc9ie0FRqjxhXgkvCymp7OL7_3POR8hnBjUD1n5d1biKxtUcmKihqYHBAZmxTvFKKa4-kBkoDhXI7ucR-ZTSCgAa2fNDcsSFanvW9TPy5w5Hk_0U0tJv6ALzE2KgvwIiNaO_D2sMmZrg6Jz9-0sfzbjFRKeBmpi93Y4mUrv7juYeX7DC-2Q99YFuSm9JJ_rk83JfOaWMU-GX0WefTsjHwYwJT1_fYzK_upxf3FS3P66_X3y7rawEmSsmpG0cik4OnemkA-UWxg6t4lINshkGjgKscS2TEkzvALnjolmonjeit-KYfNnXbuL0UNbPel1WxHE0Aadt0iUmRCcktAUVe9TGKaWIg95Evzbxt2agd9L1Sr9I1zvpGhpdpJfU2euA7WKN7n_mzXIBzvcAlisfPUZdFGGw6HxEm7Wb_LsDngELqJa3</recordid><startdate>201311</startdate><enddate>201311</enddate><creator>Wang, Ligong</creator><creator>Vieira, Renata La Rocca</creator><creator>Rybak, Leon D.</creator><creator>Babb, James S.</creator><creator>Chang, Gregory</creator><creator>Krasnokutsky, Svetlana</creator><creator>Abramson, Steven</creator><creator>Regatte, Ravinder</creator><general>Elsevier Ireland Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201311</creationdate><title>Relationship between knee alignment and T1ρ values of articular cartilage and menisci in patients with knee osteoarthritis</title><author>Wang, Ligong ; Vieira, Renata La Rocca ; Rybak, Leon D. ; Babb, James S. ; Chang, Gregory ; Krasnokutsky, Svetlana ; Abramson, Steven ; Regatte, Ravinder</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c404t-134c5de384f8a84d07dbacf67247f45ff2e30cad61440a9d0e2d235b792539c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Aged</topic><topic>Algorithms</topic><topic>Cartilage, Articular - pathology</topic><topic>Female</topic><topic>Humans</topic><topic>Image Enhancement - methods</topic><topic>Image Interpretation, Computer-Assisted - methods</topic><topic>Knee alignment</topic><topic>Knee joint</topic><topic>Knee Joint - pathology</topic><topic>Magnetic Resonance Imaging - methods</topic><topic>Male</topic><topic>Menisci, Tibial - pathology</topic><topic>Meniscus</topic><topic>Middle Aged</topic><topic>MRI</topic><topic>Osteoarthritis</topic><topic>Osteoarthritis, Knee - pathology</topic><topic>Reproducibility of Results</topic><topic>Sensitivity and Specificity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wang, Ligong</creatorcontrib><creatorcontrib>Vieira, Renata La Rocca</creatorcontrib><creatorcontrib>Rybak, Leon D.</creatorcontrib><creatorcontrib>Babb, James S.</creatorcontrib><creatorcontrib>Chang, Gregory</creatorcontrib><creatorcontrib>Krasnokutsky, Svetlana</creatorcontrib><creatorcontrib>Abramson, Steven</creatorcontrib><creatorcontrib>Regatte, Ravinder</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wang, Ligong</au><au>Vieira, Renata La Rocca</au><au>Rybak, Leon D.</au><au>Babb, James S.</au><au>Chang, Gregory</au><au>Krasnokutsky, Svetlana</au><au>Abramson, Steven</au><au>Regatte, Ravinder</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Relationship between knee alignment and T1ρ values of articular cartilage and menisci in patients with knee osteoarthritis</atitle><jtitle>European journal of radiology</jtitle><addtitle>Eur J Radiol</addtitle><date>2013-11</date><risdate>2013</risdate><volume>82</volume><issue>11</issue><spage>1946</spage><epage>1952</epage><pages>1946-1952</pages><issn>0720-048X</issn><eissn>1872-7727</eissn><abstract>To assess the relationship between knee alignment and subregional T1ρ values of the femorotibial cartilage and menisci in patients with mild (Kellgren–Lawrence grade 1) to moderate (KL3) osteoarthritis (OA) at 3T.
26 subjects with a clinical diagnosis of KL1-3 OA were included and subdivided into three subgroups: varus, valgus, and neutral. All subjects were evaluated on a 3T MR scanner. Mann–Whitney and Wilcoxon signed rank tests were performed to determine any statistically significant differences in subregional T1ρ values of femorotibial cartilage and menisci among the three subgroups of KL1-3 OA patients.
Medial femoral anterior cartilage subregion in varus group had significantly higher (p<0.05) T1ρ values than all cartilage subregions in valgus group. Medial tibial central cartilage subregion had significantly higher T1ρ values (p<0.05) than lateral tibial central cartilage subregion in varus group. The posterior horn of the medial meniscus in neutral group had significantly higher T1ρ values (p<0.0029) than all meniscus subregions in valgus group.
There exists some degree of association between knee alignment and subregional T1ρ values of femorotibial cartilage and menisci in patients with clinical OA</abstract><cop>Ireland</cop><pub>Elsevier Ireland Ltd</pub><pmid>23769189</pmid><doi>10.1016/j.ejrad.2013.05.010</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Aged Algorithms Cartilage, Articular - pathology Female Humans Image Enhancement - methods Image Interpretation, Computer-Assisted - methods Knee alignment Knee joint Knee Joint - pathology Magnetic Resonance Imaging - methods Male Menisci, Tibial - pathology Meniscus Middle Aged MRI Osteoarthritis Osteoarthritis, Knee - pathology Reproducibility of Results Sensitivity and Specificity |
title | Relationship between knee alignment and T1ρ values of articular cartilage and menisci in patients with knee osteoarthritis |
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