Frequent triple-hit expression of MYC, BCL2, and BCL6 in primary lymphoma of the central nervous system and absence of a favorable MYC(low)BCL2 (low) subgroup may underlie the inferior prognosis as compared to systemic diffuse large B cell lymphomas

Saved in:
Bibliographic Details
Published in:Acta neuropathologica 2013-10, Vol.126 (4), p.603-605
Main Authors: Brunn, Anna, Nagel, Inga, Montesinos-Rongen, Manuel, Klapper, Wolfram, Vater, Inga, Paulus, Werner, Hans, Volkmar, Blümcke, Ingmar, Weis, Joachim, Siebert, Reiner, Deckert, Martina
Format: Article
Language:English
Subjects:
Biomarkers, Tumor
Central Nervous System Neoplasms - genetics
Central Nervous System Neoplasms - pathology
Gene Expression Regulation, Neoplastic - genetics
Genes, bcl-2 - genetics
Genes, myc - genetics
Humans
Immunohistochemistry
Infant, Newborn
Lymphoma - genetics
Lymphoma - pathology
Lymphoma, Large B-Cell, Diffuse - genetics
Lymphoma, Large B-Cell, Diffuse - pathology
Prognosis
Proto-Oncogene Proteins c-bcl-6 - genetics
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:
ISSN:1432-0533
DOI:10.1007/s00401-013-1169-7