The rising incidence of celiac disease in Scotland

Although the incidence of pediatric celiac disease (CD) is increasing globally, it is uncertain whether this is attributed to improved case ascertainment or signifies a true rise. We aimed to identify all incident cases of childhood CD in southeast Scotland over the period 1990 to 2009 to assess tre...

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Bibliographic Details
Published in:Pediatrics (Evanston) 2013-10, Vol.132 (4), p.e924-e931
Main Authors: White, Lois E, Merrick, Victoria M, Bannerman, Elaine, Russell, Richard K, Basude, Dharam, Henderson, Paul, Wilson, David C, Gillett, Peter M
Format: Article
Language:English
Subjects:
Biopsy
Celiac disease
Celiac Disease - blood
Celiac Disease - diagnosis
Celiac Disease - epidemiology
Child
Child, Preschool
Children & youth
Cohort Studies
Demographic aspects
Epidemiology
Female
Humans
Incidence
Infant
Male
Pediatrics
Retrospective Studies
Risk assessment
Scotland - epidemiology
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Summary:Although the incidence of pediatric celiac disease (CD) is increasing globally, it is uncertain whether this is attributed to improved case ascertainment or signifies a true rise. We aimed to identify all incident cases of childhood CD in southeast Scotland over the period 1990 to 2009 to assess trends in total incidence and cases diagnosed as a result of (1) a classic presentation, (2) a nonclassic presentation, or (3) targeted screening. Twenty-year retrospective cohort study of case notes, pathology databases, endoscopy, and patient records for all children (
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.2013-0932