Imaging appearances for recurrent nasopharyngeal carcinoma and post-salvage nasopharyngectomy

Nasopharyngeal carcinoma (NPC) is a head and neck neoplasm that occurs in endemic numbers among people of southern Chinese descent. External beam radiation to the nasopharyngeal bed and primary draining lymph node echelons is the mainstay of treatment with concurrent cisplatin-based chemotherapy for...

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Bibliographic Details
Published in:Clinical radiology 2013-11, Vol.68 (11), p.e629-e638
Main Authors: Teo, P.T.H, Tan, N.C, Khoo, J.B.K
Format: Article
Language:English
Subjects:
Carcinoma
Fluorodeoxyglucose F18
Humans
Magnetic Resonance Imaging - methods
Nasopharyngeal Carcinoma
Nasopharyngeal Neoplasms - diagnosis
Nasopharyngeal Neoplasms - surgery
Nasopharynx - diagnostic imaging
Nasopharynx - pathology
Neoplasm Recurrence, Local - diagnosis
Positron-Emission Tomography - methods
Radiology
Radiopharmaceuticals
Sensitivity and Specificity
Tomography, X-Ray Computed - methods
Whole Body Imaging - methods
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Description
Summary:Nasopharyngeal carcinoma (NPC) is a head and neck neoplasm that occurs in endemic numbers among people of southern Chinese descent. External beam radiation to the nasopharyngeal bed and primary draining lymph node echelons is the mainstay of treatment with concurrent cisplatin-based chemotherapy for more advanced disease. Detection of residual and/or recurrent NPC has important clinical implications, as salvage protocols are available. The review aims to increase awareness of the imaging features of NPC recurrences at local and distant sites using computed tomography (CT), magnetic resonance imaging (MRI), and positron-emission tomography (PET). Important changes in imaging seen in patients after nasopharyngectomy are also discussed.
ISSN:0009-9260
1365-229X
DOI:10.1016/j.crad.2013.06.003