Templated Hierarchical Self-Assembly of Poly(p-aryltriazole) Foldamers

A biomimetic approach has been used for the templated self‐assembly of a helical poly(para‐aryltriazole) foldamer. The solvophobic folding process yields helices that further self‐assemble into long nanotubes (see picture; scale bar: 100 nm). Constructs of controlled length and chirality can be gene...

Full description

Saved in:
Bibliographic Details
Published in:Angewandte Chemie International Edition 2013-10, Vol.52 (42), p.11040-11044
Main Authors: Pfukwa, Rueben, Kouwer, Paul H. J., Rowan, Alan E., Klumperman, Bert
Format: Article
Language:English
Subjects:
Biomimetic Materials - chemistry
biomimetic synthesis
foldamers
information transfer
Molecular Conformation
Polymers - chemical synthesis
Polymers - chemistry
Protein Structure, Secondary
self-assembly
template
Templates, Genetic
Triazoles - chemical synthesis
Triazoles - chemistry
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A biomimetic approach has been used for the templated self‐assembly of a helical poly(para‐aryltriazole) foldamer. The solvophobic folding process yields helices that further self‐assemble into long nanotubes (see picture; scale bar: 100 nm). Constructs of controlled length and chirality can be generated by applying a poly(γ‐benzyl‐l‐glutamate) scaffold at the appropriate assembly conditions, mimicking tobacco mosaic virus self‐assembly.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201303135