Imported Plasmodium falciparum malaria in Istanbul, Turkey: risk factors for severe course and mortality

We describe the epidemiological, clinical features and risk factors for the morbidity and mortality of imported Plasmodium falciparum malaria cases during the last 10 years in Istanbul, Turkey. The epidemiological, clinical and laboratory data of cases in six tertiary care hospitals in Istanbul betw...

Full description

Saved in:
Bibliographic Details
Published in:Tropical doctor 2013-10, Vol.43 (4), p.129-133
Main Authors: Arslan, Ferhat, Mert, Ali, Batirel, Ayse, Inan, Asuman, Balkan, Ilker Inanc, Nazlican, Ozcan, Uzun, Cengiz, Vahaboglu, Haluk
Format: Article
Language:English
Subjects:
Adolescent
Adult
Africa
Aged
Aged, 80 and over
Female
Humans
Malaria, Falciparum - diagnosis
Malaria, Falciparum - epidemiology
Male
Middle Aged
Risk Factors
Travel
Turkey
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We describe the epidemiological, clinical features and risk factors for the morbidity and mortality of imported Plasmodium falciparum malaria cases during the last 10 years in Istanbul, Turkey. The epidemiological, clinical and laboratory data of cases in six tertiary care hospitals in Istanbul between 2002 and 2012 were analysed. Seventy patients (65 males, five females; median age 37; range: 14–84) were included. Sixty-five (93%) patients had travelled to African countries and the remaining five to other malarious countries. Seventeen (24%) had a history of previous malarial episodes; eight (13%) developed recrudescence during the first month; 22 (31%), 17 (24%), 20 (29%) and three (4%) cases had cerebral malaria, cholestatic icterus, malarial hepatitis and respiratory distress syndrome on admission, respectively. Six of 12 patients with severe falciparum malaria died. Clinically, the presence of alteration in mental status, icterus, hypoglycaemia, disseminated intravascular coagulation and malarial hepatitis were statistically significant for the development of severe malaria and mortality. Recrudescence should not be forgotten, especially in uncomplicated cases.
ISSN:0049-4755
1758-1133
DOI:10.1177/0049475513499560