Cardiac Function and Arterial Biophysical Properties in Small for Gestational Age Infants: Postnatal Manifestations of Fetal Programming

Objective To investigate the differences in cardiac function and arterial biophysical properties between term-born appropriate for gestational age (AGA) infants and small for gestational age (SGA) infants. Our hypothesis was that adaptation to intrauterine growth restriction induces changes in cardi...

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Bibliographic Details
Published in:The Journal of pediatrics 2013-11, Vol.163 (5), p.1296-1300
Main Authors: Sehgal, Arvind, FRACP, Doctor, Tejas, MD, Menahem, Samuel, FCSANZ
Format: Article
Language:English
Subjects:
Arteries - physiology
Biophysical Phenomena
birth weight
Birth Weight - physiology
blood pressure
cardiac output
Cardiovascular System
Diastole
echocardiography
Echocardiography - methods
Female
Fetal Development
Fetal Growth Retardation - physiopathology
Gestational Age
Heart - physiology
Humans
impedance
Infant, Newborn
Infant, Small for Gestational Age - physiology
infants
Male
morbidity
Pediatrics
Pregnancy
Prospective Studies
small for gestational age
Systole
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Summary:Objective To investigate the differences in cardiac function and arterial biophysical properties between term-born appropriate for gestational age (AGA) infants and small for gestational age (SGA) infants. Our hypothesis was that adaptation to intrauterine growth restriction induces changes in cardiac and arterial indices. Study design This was a prospective observational echocardiographic evaluation of cardiac and arterial indices in SGA infants and AGA infants. Demographic and echocardiographic data were compared between 20 inborn term SGA infants with birth weight
ISSN:0022-3476
1097-6833
DOI:10.1016/j.jpeds.2013.06.030