Copper-catalyzed ortho-halogenation of protected anilines

A practical Cu-catalyzed direct ortho-halogenation of anilines under aerobic conditions has been developed. The reaction shows typically excellent mono-substitution selectivity, high ortho-regiocontrol and large functional group tolerance.

Saved in:
Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2013-01, Vol.49 (94), p.11044-11046
Main Authors: Urones, Beatriz, Martínez, Ángel Manu, Rodríguez, Nuria, Arrayás, Ramón Gómez, Carretero, Juan C
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A practical Cu-catalyzed direct ortho-halogenation of anilines under aerobic conditions has been developed. The reaction shows typically excellent mono-substitution selectivity, high ortho-regiocontrol and large functional group tolerance.
ISSN:1359-7345
1364-548X
DOI:10.1039/c3cc47174h