Protein S levels and the risk of venous thrombosis: results from the MEGA case-control study

In thrombophilic families, protein S deficiency is clearly associated with venous thrombosis. We aimed to determine whether the same holds true in a population-based case-control study (n = 5317). Subjects were regarded protein S deficient when protein S levels were

Saved in:
Bibliographic Details
Published in:Blood 2013-10, Vol.122 (18), p.3210-3219
Main Authors: Pintao, Maria Carolina, Ribeiro, Daniel D., Bezemer, Irene D., Garcia, Andrea A., de Visser, Marieke C.H., Doggen, Carine J.M., Lijfering, Willem M., Reitsma, Pieter H., Rosendaal, Frits R.
Format: Article
Language:English
Subjects:
Adult
Aged
Case-Control Studies
DNA Copy Number Variations
Female
Humans
Male
Middle Aged
Mutation
Odds Ratio
Protein S - genetics
Protein S - metabolism
Protein S Deficiency - blood
Protein S Deficiency - genetics
Protein S Deficiency - metabolism
Risk Assessment
Risk Factors
Sequence Analysis, DNA
Venous Thrombosis - blood
Venous Thrombosis - metabolism
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In thrombophilic families, protein S deficiency is clearly associated with venous thrombosis. We aimed to determine whether the same holds true in a population-based case-control study (n = 5317). Subjects were regarded protein S deficient when protein S levels were
ISSN:0006-4971
1528-0020
DOI:10.1182/blood-2013-04-499335