Back Cover: Rapid, Isothermal DNA Self-Replication Induced by a Destabilizing Lesion (Angew. Chem. Int. Ed. 40/2013)

Like clockwork, rapid isothermal self-replication of oligonucleotides can be achieved using a cross-catalytic strategy as reported by J.M. Gibbs-Davis etal. in their Communication on The presence of both a destabilizing lesion in one of the replicating fragments and concentrated DNA polymerase resul...

Full description

Saved in:
Bibliographic Details
Published in:Angewandte Chemie International Edition 2013-09, Vol.52 (40), p.10660-10660
Main Authors: Kausar, Abu, Mitran, Catherine J., Li, Yimeng, Gibbs-Davis, Julianne M.
Format: Article
Language:English
Subjects:
autonomous replication
DNA replication
isothermal DNA amplification
oligonucleotides
origins of life
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Like clockwork, rapid isothermal self-replication of oligonucleotides can be achieved using a cross-catalytic strategy as reported by J.M. Gibbs-Davis etal. in their Communication on The presence of both a destabilizing lesion in one of the replicating fragments and concentrated DNA polymerase results in high reaction rates and are key to multiple replication cycles (Photo by Dean Albrecht).
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201306894