Distinctive PET/CT Features of Splenic SANT

ABSTRACTA 44-year-old woman suffered from epigastralgia for 1 month. An abdominal sonography revealed a space-occupying lesion, about 6 cm, in the spleen. Contrast-enhanced CT revealed enhanced splenic lesions. The PET/CT showed FDG-avid multiple splenic nodules with a “prunes on bread” appearance i...

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Bibliographic Details
Published in:Clinical nuclear medicine 2013-12, Vol.38 (12), p.e465-e466
Main Authors: Feng, Yu-Min, Huang, Ying Chieh, Tu, Chi-Wen, Kao, Wen-Shih, Tu, Dom-Gene
Format: Article
Language:English
Subjects:
Adult
Female
Fluorodeoxyglucose F18
Histiocytoma, Benign Fibrous - diagnostic imaging
Histiocytoma, Benign Fibrous - pathology
Humans
Male
Positron-Emission Tomography
Splenic Neoplasms - diagnostic imaging
Splenic Neoplasms - pathology
Tomography, X-Ray Computed
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Summary:ABSTRACTA 44-year-old woman suffered from epigastralgia for 1 month. An abdominal sonography revealed a space-occupying lesion, about 6 cm, in the spleen. Contrast-enhanced CT revealed enhanced splenic lesions. The PET/CT showed FDG-avid multiple splenic nodules with a “prunes on bread” appearance in the maximum-intensity-projection image (MIP image). In sectional PET/CT images, a central cold area with peripheral increased FDG uptake in the splenic nodule is visible. Because splenic malignancy was suspected, laparoscopic splenectomy was performed. Histology revealed multiple nodules with angiomatoid appearance, CD31(+), CD34(+) and HHV-8(−) in the vascular space, typical for the rare sclerosing angiomatoid nodular transformation (SANT).
ISSN:0363-9762
1536-0229
DOI:10.1097/RLU.0b013e3182867581