AC/D(eA)C rocks the polymerases

In this issue of Molecular Cell, two studies (Chen et al., 2013; Schröder et al., 2013) describe how posttranslational modification of RNA polymerases (Pol) I and II by acetylation mediates the transcriptional response to either stress or growth factors.

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Bibliographic Details
Published in:Molecular cell 2013-11, Vol.52 (3), p.287-288
Main Authors: Laitem, Clélia, Murphy, Shona
Format: Article
Language:English
Subjects:
Animals
Histones - genetics
Humans
Lysine - genetics
RNA Polymerase I - genetics
RNA Polymerase II - metabolism
Sirtuins - metabolism
Transcription Factors - metabolism
Transcription, Genetic
Transcriptional Activation - genetics
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Description
Summary:In this issue of Molecular Cell, two studies (Chen et al., 2013; Schröder et al., 2013) describe how posttranslational modification of RNA polymerases (Pol) I and II by acetylation mediates the transcriptional response to either stress or growth factors.
ISSN:1097-2765
1097-4164
DOI:10.1016/j.molcel.2013.10.025