Tissue Distribution of 2,2',4,4'-Tetrabromo[ super(14)C]diphenyl Ether ([ super(14)C]-PCDE 47) in Pike (Esox lucius) After Dietary Exposure-a Time Series Study Using Whole Body Autoradiography

The tissue distribution of radiolabeled 2,2',4,4'-tetrabromodiphenyl ether (PBDE 47) was investigated in pike Esox lucius using whole-body autoradiography. Results showed that radioactivity was present in the entire body of the exposed pike, except for the backbone. After 9 and 18 d, highe...

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Bibliographic Details
Published in:Chemosphere (Oxford) 2000-05, Vol.40 (9), p.977-977
Main Authors: Burreau, Sven, Broman, Dag, Orn, Ulrika
Format: Article
Language:English
Online Access:Get full text
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Summary:The tissue distribution of radiolabeled 2,2',4,4'-tetrabromodiphenyl ether (PBDE 47) was investigated in pike Esox lucius using whole-body autoradiography. Results showed that radioactivity was present in the entire body of the exposed pike, except for the backbone. After 9 and 18 d, highest levels of radioactivity were present in the liver, perivisceral adipose tissue, the vertebrae-surrounding tissue, and the eye capsule, and somewhat lower levels were noted in the gall bladder. Intermediate levels were recorded in brain, spinal chord, heart, and kidney, and lowest radioactivity levels were found in muscle tissue, spleen, and gills. After 36 d, radioactivity levels were lower in all organs except liver, perivisceral adipose tissue, and the vertebrae-surrounding tissue. After 65 d, radioactivity levels in liver had declined markedly, but levels remained high in the other two tissues.
ISSN:0045-6535