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Modified Blalock Taussig shunt: a not-so-simple palliative procedure
OBJECTIVES Thirty-two consecutive isolated modified Blalock Taussig (BT) shunts performed in infancy since 2004 were reviewed and analysed to identify the risk factors for shunt intervention and mortality. METHODS Sternotomy was the only approach used. Median age and weight were 10.5 (range 1-74) da...
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Published in: | European journal of cardio-thoracic surgery 2013-12, Vol.44 (6), p.1096-1102 |
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container_title | European journal of cardio-thoracic surgery |
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creator | Dirks, Verena Prêtre, René Knirsch, Walter Valsangiacomo Buechel, Emanuela R. Seifert, Burkhardt Schweiger, Martin Hübler, Michael Dave, Hitendu |
description | OBJECTIVES
Thirty-two consecutive isolated modified Blalock Taussig (BT) shunts performed in infancy since 2004 were reviewed and analysed to identify the risk factors for shunt intervention and mortality.
METHODS
Sternotomy was the only approach used. Median age and weight were 10.5 (range 1-74) days and 2.9 (1.9-4.4) kg, respectively. Shunt palliation was performed for biventricular hearts (Tetralogy of Fallot/double outlet right ventricle/transposition of great arteries_ventricular septal defect_pulmonary stenosis/pulmonary atresia_ventricular septal defect/others) in 21, and univentricular hearts in 11, patients. Hypoplastic left heart syndrome patients were excluded. Two procedures required cardiopulmonary bypass. Median shunt size was 3.5 (3-4) mm and median shunt size/kg body weight was 1.2 (0.9-1.7) mm/kg. Reduction in shunt size was necessary in 5 of 32 (16%) patients.
RESULTS
Three of 32 (9%) patients died after 3 (1-15) days due to cardiorespiratory decompensation. Lower body weight (P = 0.04) and bigger shunt size/kg of body weight (P = 0.004) were significant risk factors for mortality. Acute shunt thrombosis was observed in 3 of 32 (9%), none leading to death. Need for cardiac decongestive therapy was associated with univentricular hearts (P < 0.001), bigger shunt size (P = 0.054) and longer hospital stay (P = 0.005). Twenty-eight patients have undergone a successful shunt takedown at a median age of 5.5 (0.5-11.9) months, without late mortality.
CONCLUSIONS
Palliation with a modified BT shunt continues to be indicated despite increased thrust on primary corrective surgery. Though seemingly simple, it is associated with significant morbidity and mortality. Effective over-shunting and acute shunt thrombosis are the lingering problems of shunt therapy. |
doi_str_mv | 10.1093/ejcts/ezt172 |
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Thirty-two consecutive isolated modified Blalock Taussig (BT) shunts performed in infancy since 2004 were reviewed and analysed to identify the risk factors for shunt intervention and mortality.
METHODS
Sternotomy was the only approach used. Median age and weight were 10.5 (range 1-74) days and 2.9 (1.9-4.4) kg, respectively. Shunt palliation was performed for biventricular hearts (Tetralogy of Fallot/double outlet right ventricle/transposition of great arteries_ventricular septal defect_pulmonary stenosis/pulmonary atresia_ventricular septal defect/others) in 21, and univentricular hearts in 11, patients. Hypoplastic left heart syndrome patients were excluded. Two procedures required cardiopulmonary bypass. Median shunt size was 3.5 (3-4) mm and median shunt size/kg body weight was 1.2 (0.9-1.7) mm/kg. Reduction in shunt size was necessary in 5 of 32 (16%) patients.
RESULTS
Three of 32 (9%) patients died after 3 (1-15) days due to cardiorespiratory decompensation. Lower body weight (P = 0.04) and bigger shunt size/kg of body weight (P = 0.004) were significant risk factors for mortality. Acute shunt thrombosis was observed in 3 of 32 (9%), none leading to death. Need for cardiac decongestive therapy was associated with univentricular hearts (P < 0.001), bigger shunt size (P = 0.054) and longer hospital stay (P = 0.005). Twenty-eight patients have undergone a successful shunt takedown at a median age of 5.5 (0.5-11.9) months, without late mortality.
CONCLUSIONS
Palliation with a modified BT shunt continues to be indicated despite increased thrust on primary corrective surgery. Though seemingly simple, it is associated with significant morbidity and mortality. Effective over-shunting and acute shunt thrombosis are the lingering problems of shunt therapy.</description><identifier>ISSN: 1010-7940</identifier><identifier>EISSN: 1873-734X</identifier><identifier>DOI: 10.1093/ejcts/ezt172</identifier><identifier>PMID: 23539419</identifier><language>eng</language><publisher>Germany: Oxford University Press</publisher><subject>Blalock-Taussig Procedure - adverse effects ; Blalock-Taussig Procedure - methods ; Body Weight ; Female ; Heart Defects, Congenital - surgery ; Humans ; Infant ; Infant, Newborn ; Male ; Palliative Care - methods ; Retrospective Studies ; Risk Factors ; Sternotomy ; Thoracotomy</subject><ispartof>European journal of cardio-thoracic surgery, 2013-12, Vol.44 (6), p.1096-1102</ispartof><rights>The Author 2013. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved. 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c361t-aa32b8b8d5f4029e62911f859c1c701523188b1133d3cdba7229a45c1ffc6fd43</citedby><cites>FETCH-LOGICAL-c361t-aa32b8b8d5f4029e62911f859c1c701523188b1133d3cdba7229a45c1ffc6fd43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27922,27923</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23539419$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dirks, Verena</creatorcontrib><creatorcontrib>Prêtre, René</creatorcontrib><creatorcontrib>Knirsch, Walter</creatorcontrib><creatorcontrib>Valsangiacomo Buechel, Emanuela R.</creatorcontrib><creatorcontrib>Seifert, Burkhardt</creatorcontrib><creatorcontrib>Schweiger, Martin</creatorcontrib><creatorcontrib>Hübler, Michael</creatorcontrib><creatorcontrib>Dave, Hitendu</creatorcontrib><title>Modified Blalock Taussig shunt: a not-so-simple palliative procedure</title><title>European journal of cardio-thoracic surgery</title><addtitle>Eur J Cardiothorac Surg</addtitle><description>OBJECTIVES
Thirty-two consecutive isolated modified Blalock Taussig (BT) shunts performed in infancy since 2004 were reviewed and analysed to identify the risk factors for shunt intervention and mortality.
METHODS
Sternotomy was the only approach used. Median age and weight were 10.5 (range 1-74) days and 2.9 (1.9-4.4) kg, respectively. Shunt palliation was performed for biventricular hearts (Tetralogy of Fallot/double outlet right ventricle/transposition of great arteries_ventricular septal defect_pulmonary stenosis/pulmonary atresia_ventricular septal defect/others) in 21, and univentricular hearts in 11, patients. Hypoplastic left heart syndrome patients were excluded. Two procedures required cardiopulmonary bypass. Median shunt size was 3.5 (3-4) mm and median shunt size/kg body weight was 1.2 (0.9-1.7) mm/kg. Reduction in shunt size was necessary in 5 of 32 (16%) patients.
RESULTS
Three of 32 (9%) patients died after 3 (1-15) days due to cardiorespiratory decompensation. Lower body weight (P = 0.04) and bigger shunt size/kg of body weight (P = 0.004) were significant risk factors for mortality. Acute shunt thrombosis was observed in 3 of 32 (9%), none leading to death. Need for cardiac decongestive therapy was associated with univentricular hearts (P < 0.001), bigger shunt size (P = 0.054) and longer hospital stay (P = 0.005). Twenty-eight patients have undergone a successful shunt takedown at a median age of 5.5 (0.5-11.9) months, without late mortality.
CONCLUSIONS
Palliation with a modified BT shunt continues to be indicated despite increased thrust on primary corrective surgery. Though seemingly simple, it is associated with significant morbidity and mortality. Effective over-shunting and acute shunt thrombosis are the lingering problems of shunt therapy.</description><subject>Blalock-Taussig Procedure - adverse effects</subject><subject>Blalock-Taussig Procedure - methods</subject><subject>Body Weight</subject><subject>Female</subject><subject>Heart Defects, Congenital - surgery</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Male</subject><subject>Palliative Care - methods</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Sternotomy</subject><subject>Thoracotomy</subject><issn>1010-7940</issn><issn>1873-734X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNp9kDtPwzAURi0EoqWwMaNsMBDqa-dhs5XylIpYisQWOX6Ai1OHOEGCX08ghZHpfsPRudJB6BDwGWBOp3ol2zDVny3kZAuNgeU0zmnytN1vDDjOeYJHaC-EFcY4oyTfRSNCU8oT4GN0ee-VNVar6MIJ5-VrtBRdCPY5Ci_duj2PRLT2bRx8HGxVOx3VwjkrWvvez8ZLrbpG76MdI1zQB5s7QY_XV8v5bbx4uLmbzxaxpBm0sRCUlKxkKjUJJlxnhAMYlnIJMseQEgqMlQCUKipVKXJCuEhSCcbIzKiETtDJ4O0_v3U6tEVlg9TOibX2XSggSRmwjJG0R08HVDY-hEabom5sJZqPAnDx3a346VYM3Xr8aGPuykqrP_g3VA8cD4Dv6v9VX4f1d8E</recordid><startdate>201312</startdate><enddate>201312</enddate><creator>Dirks, Verena</creator><creator>Prêtre, René</creator><creator>Knirsch, Walter</creator><creator>Valsangiacomo Buechel, Emanuela R.</creator><creator>Seifert, Burkhardt</creator><creator>Schweiger, Martin</creator><creator>Hübler, Michael</creator><creator>Dave, Hitendu</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201312</creationdate><title>Modified Blalock Taussig shunt: a not-so-simple palliative procedure</title><author>Dirks, Verena ; Prêtre, René ; Knirsch, Walter ; Valsangiacomo Buechel, Emanuela R. ; Seifert, Burkhardt ; Schweiger, Martin ; Hübler, Michael ; Dave, Hitendu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c361t-aa32b8b8d5f4029e62911f859c1c701523188b1133d3cdba7229a45c1ffc6fd43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Blalock-Taussig Procedure - adverse effects</topic><topic>Blalock-Taussig Procedure - methods</topic><topic>Body Weight</topic><topic>Female</topic><topic>Heart Defects, Congenital - surgery</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Male</topic><topic>Palliative Care - methods</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Sternotomy</topic><topic>Thoracotomy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dirks, Verena</creatorcontrib><creatorcontrib>Prêtre, René</creatorcontrib><creatorcontrib>Knirsch, Walter</creatorcontrib><creatorcontrib>Valsangiacomo Buechel, Emanuela R.</creatorcontrib><creatorcontrib>Seifert, Burkhardt</creatorcontrib><creatorcontrib>Schweiger, Martin</creatorcontrib><creatorcontrib>Hübler, Michael</creatorcontrib><creatorcontrib>Dave, Hitendu</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of cardio-thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dirks, Verena</au><au>Prêtre, René</au><au>Knirsch, Walter</au><au>Valsangiacomo Buechel, Emanuela R.</au><au>Seifert, Burkhardt</au><au>Schweiger, Martin</au><au>Hübler, Michael</au><au>Dave, Hitendu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Modified Blalock Taussig shunt: a not-so-simple palliative procedure</atitle><jtitle>European journal of cardio-thoracic surgery</jtitle><addtitle>Eur J Cardiothorac Surg</addtitle><date>2013-12</date><risdate>2013</risdate><volume>44</volume><issue>6</issue><spage>1096</spage><epage>1102</epage><pages>1096-1102</pages><issn>1010-7940</issn><eissn>1873-734X</eissn><abstract>OBJECTIVES
Thirty-two consecutive isolated modified Blalock Taussig (BT) shunts performed in infancy since 2004 were reviewed and analysed to identify the risk factors for shunt intervention and mortality.
METHODS
Sternotomy was the only approach used. Median age and weight were 10.5 (range 1-74) days and 2.9 (1.9-4.4) kg, respectively. Shunt palliation was performed for biventricular hearts (Tetralogy of Fallot/double outlet right ventricle/transposition of great arteries_ventricular septal defect_pulmonary stenosis/pulmonary atresia_ventricular septal defect/others) in 21, and univentricular hearts in 11, patients. Hypoplastic left heart syndrome patients were excluded. Two procedures required cardiopulmonary bypass. Median shunt size was 3.5 (3-4) mm and median shunt size/kg body weight was 1.2 (0.9-1.7) mm/kg. Reduction in shunt size was necessary in 5 of 32 (16%) patients.
RESULTS
Three of 32 (9%) patients died after 3 (1-15) days due to cardiorespiratory decompensation. Lower body weight (P = 0.04) and bigger shunt size/kg of body weight (P = 0.004) were significant risk factors for mortality. Acute shunt thrombosis was observed in 3 of 32 (9%), none leading to death. Need for cardiac decongestive therapy was associated with univentricular hearts (P < 0.001), bigger shunt size (P = 0.054) and longer hospital stay (P = 0.005). Twenty-eight patients have undergone a successful shunt takedown at a median age of 5.5 (0.5-11.9) months, without late mortality.
CONCLUSIONS
Palliation with a modified BT shunt continues to be indicated despite increased thrust on primary corrective surgery. Though seemingly simple, it is associated with significant morbidity and mortality. Effective over-shunting and acute shunt thrombosis are the lingering problems of shunt therapy.</abstract><cop>Germany</cop><pub>Oxford University Press</pub><pmid>23539419</pmid><doi>10.1093/ejcts/ezt172</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Blalock-Taussig Procedure - adverse effects Blalock-Taussig Procedure - methods Body Weight Female Heart Defects, Congenital - surgery Humans Infant Infant, Newborn Male Palliative Care - methods Retrospective Studies Risk Factors Sternotomy Thoracotomy |
title | Modified Blalock Taussig shunt: a not-so-simple palliative procedure |
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