Wall shear stress distribution at the carotid bifurcation: influence of eversion carotid endarterectomy

• Published in: European radiology 2013-12, Vol.23 (12), p.3361-3369
• Main Authors: Harloff, A., Berg, S., Barker, A. J., Schöllhorn, J., Schumacher, M., Weiller, C., Markl, M.
• Format: Article
• Language: English
• Subjects: Aged; Atherosclerosis; Blood Flow Velocity; Carotid arteries; Carotid Artery, Internal - pathology; Carotid Artery, Internal - physiopathology; Carotid Artery, Internal - surgery; Carotid Stenosis - diagnosis; Carotid Stenosis - physiopathology; Carotid Stenosis - surgery; Contrast agents; Diagnostic Radiology; Endarterectomy, Carotid; Feasibility Studies; Female; Hemodynamics; Humans; Imaging; Internal Medicine; Interventional Radiology; Magnetic Resonance; Magnetic Resonance Imaging; Male; Medicine; Medicine & Public Health; Neuroradiology; Prospective Studies; Radiology; Shear stress; Stress, Mechanical; Surgery; Systole; Ultrasound; Veins & arteries
• ISSN: 0938-7994; 1432-1084
• DOI: 10.1007/s00330-013-2953-4

Objectives To test the feasibility of four-dimensional (4D) flow MRI to quantify the systolic wall shear stress (WSS systole ) and oscillatory shear index (OSI) in high-grade internal carotid artery (ICA) stenosis before and after endarterectomy (CEA). Methods Twenty patients with ≥60 % ICA stenosis were prospectively and consequently included. Four-dimensional flow MRI was used to measure individual time-resolved 3D blood flow velocities. Segmental WSS systole and OSI were derived at eight wall segments in analysis planes positioned along the ICA, common (CCA) and external carotid artery (ECA). Results Regional WSS systole of all patients decreased after CEA ( P